Mass Spectrometry Analysis of Protonated Marine Natural Product Seriniquinone
Data
2018
Autores
Silva, Rodrigo Moreira da
Guaratini, Thais
Jimenez, Paula Christine [UNIFESP]
Fenical, William
Costa-Lotufo, Leticia Veras
Vessecchi, Ricardo
Lopes, Norberto Peporine
Orientadores
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Seriniquinone is a natural quinone isolated from a rare marine bacterium of the genus Serinicoccus. This secondary metabolite has been shown to have anticancer properties, which has raised attention of the scientific community. In this short report, we present the first investigation of the gas-phase chemistry fragmentation reactions of seriniquinone in electrospray ionization tandem mass spectrometry (ESI-MS/MS), to be further applied in pharmacokinetics and metabolism studies. All the proposals herein were supported by computational chemistry.
Descrição
Citação
Journal Of The Brazilian Chemical Society. Sao Paulo, v. 29, n. 5, p. 1162-1166, 2018.