Mass Spectrometry Analysis of Protonated Marine Natural Product Seriniquinone

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dc.citation.issue5
dc.citation.volumev. 29
dc.contributor.authorSilva, Rodrigo Moreira da
dc.contributor.authorGuaratini, Thais
dc.contributor.authorJimenez, Paula Christine [UNIFESP]
dc.contributor.authorFenical, William
dc.contributor.authorCosta-Lotufo, Leticia Veras
dc.contributor.authorVessecchi, Ricardo
dc.contributor.authorLopes, Norberto Peporine
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.coverageSao Paulo
dc.date.accessioned2020-07-20T16:30:58Z
dc.date.available2020-07-20T16:30:58Z
dc.date.issued2018
dc.description.abstractSeriniquinone is a natural quinone isolated from a rare marine bacterium of the genus Serinicoccus. This secondary metabolite has been shown to have anticancer properties, which has raised attention of the scientific community. In this short report, we present the first investigation of the gas-phase chemistry fragmentation reactions of seriniquinone in electrospray ionization tandem mass spectrometry (ESI-MS/MS), to be further applied in pharmacokinetics and metabolism studies. All the proposals herein were supported by computational chemistry.en
dc.description.affiliationUniv Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, NPPNS, BR-14040903 Ribeirao Preto, SP, Brazil
dc.description.affiliationLychnoflora Pesquisa & Desenvolvimento Prod Nat L, Campus USP, Ribeirao Preto, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Ciencias Mar, BR-11070100 Santos, SP, Brazil
dc.description.affiliationUniv Calif San Diego, Scripps Inst Oceanog, CMBB, 9500 Gilman Dr 0204, La Jolla, CA 92093 USA
dc.description.affiliationUniv Sao Paulo, Dept Farmacol, Inst Ciencias Biomed, BR-05508900 Sao Paulo, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040901 Ribeirao Preto, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Ciencias Mar, BR-11070100 Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIDFAPESP: 2014/50265-3
dc.format.extent1162-1166
dc.identifierhttps://dx.doi.org/10.21577/0103-5053.20180037
dc.identifier.citationJournal Of The Brazilian Chemical Society. Sao Paulo, v. 29, n. 5, p. 1162-1166, 2018.
dc.identifier.doi10.21577/0103-5053.20180037
dc.identifier.fileS0103-50532018000501162.pdf
dc.identifier.issn0103-5053
dc.identifier.scieloS0103-50532018000501162
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55616
dc.identifier.wosWOS:000427641700024
dc.language.isoeng
dc.publisherSoc Brasileira Quimica
dc.relation.ispartofJournal Of The Brazilian Chemical Society
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSerinicoccusen
dc.subjectSeriniquinoneen
dc.subjectElectrospray ionization mass spectrometryen
dc.subjectQuinonesen
dc.subjectComputational chemistryen
dc.titleMass Spectrometry Analysis of Protonated Marine Natural Product Seriniquinoneen
dc.typeinfo:eu-repo/semantics/article
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