Mass Spectrometry Analysis of Protonated Marine Natural Product Seriniquinone

Mass Spectrometry Analysis of Protonated Marine Natural Product Seriniquinone

Author Silva, Rodrigo M. da Google Scholar
Guaratini, Thais Google Scholar
Jimenez, Paula Christine Autor UNIFESP Google Scholar
Fenical, William Google Scholar
Costa-Lotufo, Leticia V. Google Scholar
Vessecchi, Ricardo Google Scholar
Lopes, Norberto P. Google Scholar
Abstract Seriniquinone is a natural quinone isolated from a rare marine bacterium of the genus Serinicoccus. This secondary metabolite has been shown to have anticancer properties, which has raised attention of the scientific community. In this short report, we present the first investigation of the gas-phase chemistry fragmentation reactions of seriniquinone in electrospray ionization tandem mass spectrometry (ESI-MS/MS), to be further applied in pharmacokinetics and metabolism studies. All the proposals herein were supported by computational chemistry.
Keywords Serinicoccus
seriniquinone
electrospray ionization mass spectrometry
quinones
computational chemistry
xmlui.dri2xhtml.METS-1.0.item-coverage Sao Paulo
Language English
Sponsor FAPESP
CAPES
CNPq
Grant number FAPESP: 2014/50265-3
Date 2018
Published in Journal Of The Brazilian Chemical Society. Sao Paulo, v. 29, n. 5, p. 1162-1166, 2018.
ISSN 0103-5053 (Sherpa/Romeo, impact factor)
Publisher Soc Brasileira Quimica
Extent 1162-1166
Origin http://dx.doi.org/10.21577/0103-5053.20180037
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000427641700024
SciELO ID S0103-50532018000501162 (statistics in SciELO)
URI https://repositorio.unifesp.br/handle/11600/55616

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