Queixa subjetiva da memória em brasileiros acima dos 50 anos: análise da linha de base do estudo ELSI-Brasil
Data
2023-11-14
Autores
Pinho, Pedro José de Moraes Rebello 
Orientadores
Ferri, Cleusa Pinheiro
Tipo
Dissertação de mestrado
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Objetivo: Avaliar a prevalência de queixas subjetivas de memória (QSM) e a
associação destas com fatores sociais, de saúde e o desempenho cognitivo objetivo
em uma amostra representativa de brasileiros acima dos 50 anos. Também entre os
indivíduos com QSM, estimar a associação de fatores sociais e de saúde com prejuízo
objetivo de memória.
Métodos: Análise da linha de base do Estudo Longitudinal sobre a Saúde do Idoso
(ELSI-Brasil), com 7831 indivíduos, que foram questionados sobre a autopercepção
da memória. Foi realizada uma regressão logística com o objetivo de avaliar a
associação entre características demográficas, variáveis de saúde, performance
objetiva da memória e incapacidade em atividades básicas, instrumentais e
avançadas de vida diária com a presença de QSM. Depois foi realizado um teste de
interação por sexo/gênero para a idade e performance de memória. Por último, foi
realizada uma regressão logística com objetivo de avaliar a associação entre
características demográficas, variáveis de saúde, e incapacidade em ABVDs, AIVDs
e AAVDs com prejuízo da memória em indivíduos com QSM.
Resultados: 42% da amostra apresentava QSM, com uma prevalência crescente pela
idade em homens e decrescente em mulheres. A presença de QSM estava
relacionada a menor performance objetiva da memória, ser do sexo/gênero feminino,
menor idade, menor escolaridade, maior número de doenças crônicas, menor
incapacidade em ABVDs, maior incapacidade em AIVDs, pior percepção de saúde e
maior número de sintomas depressivos. O teste de interação por sexo/gênero
encontrou que a menor idade estava associada a QSM apenas em mulheres,
enquanto a menor performance objetiva da memória estava associada a QSM apenas
em homens. A prevalência de prejuízo objetivo de memória foi de 24,7% nos
participantes com QSM e similar em homens e mulheres. O prejuízo objetivo da
memória em indivíduos com QSM estava associado a maior escolaridade, menor
renda per capita, maior incapacidade em AIVDs e AAVDs, pior percepção da saúde e
mais sintomas depressivos.
Conclusões: As QSM são comuns na população brasileira acima de 50 anos e estão
associadas a fatores sociodemográficos e de saúde, com diferentes padrões e
associações para homens e mulheres. Apenas um em quatro participantes com QSM
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tinham de fato prejuízo objetivo da memória, que estava associado a uma maior
escolaridade, menor renda domiciliar, maior incapacidade nas AAVDs e AIVDs, além
de mais sintomas depressivos. Análises longitudinais futuras são necessárias para
uma melhor compreensão da relação entre as QSM e conversões futuras para
prejuízo cognitivo ou demência, incluindo a real proporção de conversão, assim como
seus determinantes.
Objective: To estimate the prevalence of subjective memory complaints (SMCs), to assess its association with social-demographic and health factors, and objective memory performance in a large and nationally representative sample of Brazilians aged 50 years and above. And, among individuals with SMCs, to estimate the association of social-demographic and health factors with objective memory impairment. Methods: 7831 participants from baseline data from the ELSI-Brazil cohort, a representative sample of Brazilians over the age of 50, who were asked to rate their memory and divided into having SMCs or not. Logistic regression models were used to estimate the association of demographic characteristics, health related factors, objective memory performance and disability in basic, instrumental, and advanced activities of daily living associated with the presence of SMCs. Interaction test of sex/gender with the age and memory performance was also performed. Finally, logistic regression models were used in individuals with SMCs, aiming to estimate the association of sociodemographic, health-related, and disability in b-ADL, i-ADL and aADL with memory impairment. Results: 42% of the sample had SMC, with decreasing prevalence with age in women, while increasing in men. Presence of SMCs was associated with lower objective memory performance, being a woman, having lower age, lower education, higher number of chronic illnesses, lower disability in b-ADL, higher disability in i-ADL, worse health perception, and higher depressive symptoms. Interaction test revealed that lower age was associated with SMCs only in women, while objective memory was associated only in men. The prevalence of objective memory impairment in participants with QSM was 24.7% and was similar among women and men. Objective memory impairment in individuals with SMCs was associated with lower education, lower household income per capita, higher disability in i-ADL and a-ADL, worse health perception, and higher depressive symptoms. Conclusions: SMCs are common in the Brazilian older population and are associated with health and sociodemographic factors, with different patterns and associations in men and women. Only one in four participants with SMCs had objective memory impairment which was associated with higher education, lower income, higher capacity xiii on daily activities and depressive symptoms. Future longitudinal analysis are necessary for a better understanding of the relationship between SMC future conversion to cognitive impairment and dementia, including not only the real proportion of conversion but also its determinants
Objective: To estimate the prevalence of subjective memory complaints (SMCs), to assess its association with social-demographic and health factors, and objective memory performance in a large and nationally representative sample of Brazilians aged 50 years and above. And, among individuals with SMCs, to estimate the association of social-demographic and health factors with objective memory impairment. Methods: 7831 participants from baseline data from the ELSI-Brazil cohort, a representative sample of Brazilians over the age of 50, who were asked to rate their memory and divided into having SMCs or not. Logistic regression models were used to estimate the association of demographic characteristics, health related factors, objective memory performance and disability in basic, instrumental, and advanced activities of daily living associated with the presence of SMCs. Interaction test of sex/gender with the age and memory performance was also performed. Finally, logistic regression models were used in individuals with SMCs, aiming to estimate the association of sociodemographic, health-related, and disability in b-ADL, i-ADL and aADL with memory impairment. Results: 42% of the sample had SMC, with decreasing prevalence with age in women, while increasing in men. Presence of SMCs was associated with lower objective memory performance, being a woman, having lower age, lower education, higher number of chronic illnesses, lower disability in b-ADL, higher disability in i-ADL, worse health perception, and higher depressive symptoms. Interaction test revealed that lower age was associated with SMCs only in women, while objective memory was associated only in men. The prevalence of objective memory impairment in participants with QSM was 24.7% and was similar among women and men. Objective memory impairment in individuals with SMCs was associated with lower education, lower household income per capita, higher disability in i-ADL and a-ADL, worse health perception, and higher depressive symptoms. Conclusions: SMCs are common in the Brazilian older population and are associated with health and sociodemographic factors, with different patterns and associations in men and women. Only one in four participants with SMCs had objective memory impairment which was associated with higher education, lower income, higher capacity xiii on daily activities and depressive symptoms. Future longitudinal analysis are necessary for a better understanding of the relationship between SMC future conversion to cognitive impairment and dementia, including not only the real proportion of conversion but also its determinants
Descrição
Citação
PINHO, Pedro José de Moraes Rebello. Queixa subjetiva da memória em brasileiros acima dos 50 anos: análise da linha de base do estudo ELSI-Brasil. 2023. 82 f. Dissertação (Mestrado em Psiquiatria e Psicologia Médica) - Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP). São Paulo, 2023.