Criptococcose: causas, tratamento e epidemiologia
Data
2020-10-05
Autores
Oliveira, Letícia Vitória Venâncio de 
Orientadores
Ferreira, Karen Spadari
Tipo
Trabalho de conclusão de curso
Título da Revista
ISSN da Revista
Título de Volume
Resumo
A criptococcose é uma infecção fúngica oportunista que atinge principalmente os
pulmões e o sistema nervoso central. A infecção se dá através da inalação de um
esporo do fungo ou levedura dessecada que ao chegar ao pulmão pode disseminarse por todo o organismo, principalmente ao SNC pelo qual possui tropismo. A
criptococcose é uma doença causada por duas espécies: C. neoformans e C. gattii.
O fungo C. neoformans é comumente reportada em pessoas portadoras de HIVAIDS ou com imunodepressão, enquanto que a doença por C. gattii atinge
principalmente pessoas imunocompetentes. Estudos demostram que a principal
fonte ambiental do C. neoformans são as fezes de aves como pombos, galinhas e
perus, por sua vez, o C. gattii é comumente isolada de algumas espécies de árvores.
A criptococcose é uma doença que ocorre globalmente e que apresenta altas taxas
de mortalidade. O continente Africano é a região em que ocorre a maior taxa de
óbitos, visto a grande prevalência de HIV na população. O presente trabalho tem
como objetivo levantar os principais pontos sobre a doença e seus agentes
etiológicos, através de uma revisão bibliográfica na base cientifica PubMed, como:
causas da doença, sintomas, epidemiologia e tratamento da doença, bem como
outros dados pertinentes a essa micose sistêmica.
Cryptococcosis is an opportunistic fungal infection that mainly affects the lungs and the central nervous system. The infection occurs through the inhalation of a spore of the fungus or desiccated yeast that, upon reaching the lung can spread throughout the body, mainly to the CNS by which it has tropism. Cryptococcosis is a disease caused by two species: C. neoformans and C. gattii. The fungus C. neoformans is commonly reported in people with HIV-AIDS or with immunodepression, whereas the disease by C. gattii affects mainly immunocompetent people. Studies show that the main environmental source of C. neoformans is a bird droppings like pigeons, chickens and turkeys, while C. gattii is found in some species of trees. Cryptococcosis is a disease that occurs globally and has high mortality rates. African continent is the region where the highest death rate occurs because there is a high prevalence of HIV in the population. The present work has a goal, to gather the main points of the disease and its etiological agents, through a bibliographic review in the scientific base PubMed, such the causes of the disease, symptoms, epidemiology and treatment of the disease, as well as other data relevant to this opportunistic fungal disease.
Cryptococcosis is an opportunistic fungal infection that mainly affects the lungs and the central nervous system. The infection occurs through the inhalation of a spore of the fungus or desiccated yeast that, upon reaching the lung can spread throughout the body, mainly to the CNS by which it has tropism. Cryptococcosis is a disease caused by two species: C. neoformans and C. gattii. The fungus C. neoformans is commonly reported in people with HIV-AIDS or with immunodepression, whereas the disease by C. gattii affects mainly immunocompetent people. Studies show that the main environmental source of C. neoformans is a bird droppings like pigeons, chickens and turkeys, while C. gattii is found in some species of trees. Cryptococcosis is a disease that occurs globally and has high mortality rates. African continent is the region where the highest death rate occurs because there is a high prevalence of HIV in the population. The present work has a goal, to gather the main points of the disease and its etiological agents, through a bibliographic review in the scientific base PubMed, such the causes of the disease, symptoms, epidemiology and treatment of the disease, as well as other data relevant to this opportunistic fungal disease.