Does the Capsule Interfere with Performance of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Cryptococcus neoformans and Cryptococcus gattii?
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Data
2016
Autores
Thomaz, Danilo Y.
Grenfell, Rafaella C. [UNIFESP]
Vidal, Monica S. M.
Giudice, Mauro C.
Del Negro, Gilda M. B.
Juliano, Luiz [UNIFESP]
Benard, Gil
de Almeida Junior, Joao N.
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We described the impact of the capsule size for Cryptococcus neoformans and Cryptococcus gattii identification at the species level by Bruker matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). After experimental capsule size modulation, we observed that reducing the capsule size resulted in improved identification by Bruker MALDI-TOF MS across all of the reference strains analyzed.
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Journal Of Clinical Microbiology. Washington, v. 54, n. 2, p. 474-477, 2016.