Intensity and physiological responses to the 6-minute walk test in middle-aged and older adults: a comparison with cardiopulmonary exercise testing

Intensity and physiological responses to the 6-minute walk test in middle-aged and older adults: a comparison with cardiopulmonary exercise testing

Author Sperandio, Evandro Fornias Autor UNIFESP Google Scholar
Arantes, Rodolfo Leite Google Scholar
Matheus, Agatha Caveda Autor UNIFESP Google Scholar
Silva, Rodrigo Pereira da Autor UNIFESP Google Scholar
Lauria, Vinicius Tonon Autor UNIFESP Google Scholar
Romiti, Marcello Google Scholar
Gagliardi, Antonio Ricardo de Toledo Google Scholar
Dourado, Victor Zuniga Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Inst Med Cardiovasc Angiocorpore
Abstract The 6-minute walk test (6MWT) is a simple field test that is widely used in clinical settings to assess functional exercise capacity. However, studies with healthy subjects are scarce. We hypothesized that the 6MWT might be useful to assess exercise capacity in healthy subjects. the purpose of this study was to evaluate 6MWT intensity in middle-aged and older adults, as well as to develop a simple equation to predict oxygen uptake (V) over dotO(2)) from the 6-min walk distance (6MWD). Eighty-six participants, 40 men and 46 women, 40-74 years of age and with a mean body mass index of 28 +/- 6 kg/m(2), performed the 6MWT according to American Thoracic Society guidelines. Physiological responses were evaluated during the 6MWT using a K4b2 Cosmed telemetry gas analyzer. On a different occasion, the subjects performed ramp protocol cardiopulmonary exercise testing (CPET) on a treadmill. Peak (V) over dotO(2) in the 6MWT corresponded to 78 +/- 13% of the peak (V) over dotO(2) during CPET, and the maximum heart rate corresponded to 80 +/- 23% of that obtained in CPET. Peak (V) over dotO(2) in CPET was adequately predicted by the 6MWD by a linear regression equation: (V) over dotO(2) mL.min(-1).kg(-1) = -2.863 + (0.0563 x 6MWD(m)) (R-2 = 0.76). the 6MWT represents a moderate-to-high intensity activity in middle-aged and older adults and proved to be useful for predicting cardiorespiratory fitness in the present study. Our results suggest that the 6MWT may also be useful in asymptomatic individuals, and its use in walk-based conditioning programs should be encouraged.
Keywords Exercise
Gas exchange
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number FAPESP: 2007/08673-3
Date 2015-04-01
Published in Brazilian Journal of Medical and Biological Research. São Paulo: Assoc Bras Divulg Cientifica, v. 48, n. 4, p. 349-353, 2015.
ISSN 0100-879X (Sherpa/Romeo, impact factor)
Publisher Assoc Bras Divulg Cientifica
Extent 349-353
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000354184800010
SciELO ID S0100-879X2015000400349 (statistics in SciELO)

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