Intensity and physiological responses to the 6-minute walk test in middle-aged and older adults: a comparison with cardiopulmonary exercise testing

dc.contributor.authorSperandio, Evandro Fornias [UNIFESP]
dc.contributor.authorArantes, Rodolfo Leite
dc.contributor.authorMatheus, Agatha Caveda [UNIFESP]
dc.contributor.authorSilva, Rodrigo Pereira da [UNIFESP]
dc.contributor.authorLauria, Vinicius Tonon [UNIFESP]
dc.contributor.authorRomiti, Marcello
dc.contributor.authorGagliardi, Antonio Ricardo de Toledo
dc.contributor.authorDourado, Victor Zuniga [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionInst Med Cardiovasc Angiocorpore
dc.date.accessioned2016-01-24T14:40:17Z
dc.date.available2016-01-24T14:40:17Z
dc.date.issued2015-04-01
dc.description.abstractThe 6-minute walk test (6MWT) is a simple field test that is widely used in clinical settings to assess functional exercise capacity. However, studies with healthy subjects are scarce. We hypothesized that the 6MWT might be useful to assess exercise capacity in healthy subjects. the purpose of this study was to evaluate 6MWT intensity in middle-aged and older adults, as well as to develop a simple equation to predict oxygen uptake (V) over dotO(2)) from the 6-min walk distance (6MWD). Eighty-six participants, 40 men and 46 women, 40-74 years of age and with a mean body mass index of 28 +/- 6 kg/m(2), performed the 6MWT according to American Thoracic Society guidelines. Physiological responses were evaluated during the 6MWT using a K4b2 Cosmed telemetry gas analyzer. On a different occasion, the subjects performed ramp protocol cardiopulmonary exercise testing (CPET) on a treadmill. Peak (V) over dotO(2) in the 6MWT corresponded to 78 +/- 13% of the peak (V) over dotO(2) during CPET, and the maximum heart rate corresponded to 80 +/- 23% of that obtained in CPET. Peak (V) over dotO(2) in CPET was adequately predicted by the 6MWD by a linear regression equation: (V) over dotO(2) mL.min(-1).kg(-1) = -2.863 + (0.0563 x 6MWD(m)) (R-2 = 0.76). the 6MWT represents a moderate-to-high intensity activity in middle-aged and older adults and proved to be useful for predicting cardiorespiratory fitness in the present study. Our results suggest that the 6MWT may also be useful in asymptomatic individuals, and its use in walk-based conditioning programs should be encouraged.en
dc.description.affiliationUniversidade Federal de São Paulo, Lab Epidemiol & Movimento Humano EPIMOV, Dept Ciencias Movimento Humano, Santos, SP, Brazil
dc.description.affiliationInst Med Cardiovasc Angiocorpore, Santos, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Lab Epidemiol & Movimento Humano EPIMOV, Dept Ciencias Movimento Humano, Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIDFAPESP: 2007/08673-3
dc.format.extent349-353
dc.identifierhttps://dx.doi.org/10.1590/1414-431X20144235
dc.identifier.citationBrazilian Journal of Medical and Biological Research. São Paulo: Assoc Bras Divulg Cientifica, v. 48, n. 4, p. 349-353, 2015.
dc.identifier.doi10.1590/1414-431X20144235
dc.identifier.fileS0100-879X2015000400349.pdf
dc.identifier.issn0100-879X
dc.identifier.scieloS0100-879X2015000400349
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/38918
dc.identifier.wosWOS:000354184800010
dc.language.isoeng
dc.publisherAssoc Bras Divulg Cientifica
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.rightsAcesso aberto
dc.subjectExerciseen
dc.subjectWalkingen
dc.subjectGas exchangeen
dc.titleIntensity and physiological responses to the 6-minute walk test in middle-aged and older adults: a comparison with cardiopulmonary exercise testingen
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