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- ItemAcesso aberto (Open Access)Associação do eletrocardiograma com diabete melito e síndrome metabólica em nipo-brasileiros(Sociedade Brasileira de Cardiologia - SBC, 2009-05-01) Brollo, Luigi [UNIFESP]; Bombig, Maria Teresa Nogueira [UNIFESP]; Mazzaro, Cleber do Lago [UNIFESP]; Francisco, Yoná Afonso [UNIFESP]; Fonseca, Francisco Antonio Helfenstein [UNIFESP]; Carvalho, Antonio Carlos [UNIFESP]; Harima, Helena [UNIFESP]; Hirai, Amélia [UNIFESP]; Póvoa, Rui Manuel dos Santos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Japanese-Brazilian Diabetes Study GroupBACKGROUND: When the Japanese immigrated to the Americas, they were subjected to Westernization, with a great change in lifestyle, specially in dietary habits, and this may explain the increase in the incidence of diabetes mellitus (DM), metabolic syndrome (MS) and cardiovascular disease among them. OBJECTIVE: To study the presence of myocardial necrosis and left ventricular hypertrophy (LVH) in a population of Japanese-Brazilians, using the ECG and its relationship with DM and MS. METHODS: This was a cross-sectional study which evaluated 1,042 Japanese-Brazilians aged 30 or over, 202 of them born in Japan (Issei) and 840 of them born in Brazil (Nissei), from the second phase of the Japanese-Brazilian Diabetes Study Group initiated in 2000. MS was defined according to the NCEP-ATP III criteria modified for the Japanese. DM and MS were associated with the presence of myocardial necrosis (according to the Minnesota criteria) and LVH (according the Perugia score on the ECG). The statistic chi square method was used to reject the null hypothesis.? RESULTS: Of the 1,042 participants, 35.3% had DM (38.6% of the Issei and 34.5% of the Nissei); 51.8% had MS (59.4% of the Issei and 50.0% of the Nissei). The presence of an inactive zone in the diabetic Issei group was not statistically significant when compared to the non-diabetic group, but among the diabetic Nissei group an inactive zone was present in 7.5% of them. There was a statistically significant correlation between MS and LVH in the Issei and Nissei groups. CONCLUSION: Metabolic disorders presented a high prevalence in Japanese-Brazilians with significant correlations with necrosis and hypertrophy on the ECG.
- ItemAcesso aberto (Open Access)Associação do eletrocardiograma com o diabetes mellitus e a síndrome metabólica em nipo-brasileiros(Universidade Federal de São Paulo (UNIFESP), 2008) Brollo, Luigi [UNIFESP]; Póvoa, Rui Manuel dos Santos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objetivo: Analisar a presença de necrose miocárdica e hipertrofia ventricular esquerda (HVE) pelo ECG e sua relação com DM e SM em população de nipo-brasileiros. Métodos: Estudo transversal que avaliou 1042 nipo-brasileiros acima de 30 anos, 202 nascidos no Japão (isseis) e 840 nascidos no Brasil (nisseis), provenientes da segunda fase do estudo Japanese-Brazilian Diabetes Study Group iniciado em 2000. A SM foi definida pelos critérios da NCEP-ATP III modificados para os japoneses. A presença de DM e SM se associou ao encontro de necrose miocárdica pelo critério de Minnesota e de HVE pelo critério de Perugia no ECG. Utilizou-se o método estatístico do quiquadrado e t pareado para rejeição da hipótese de nulidade. Resultados. Dos 1042 participantes 35,3% tinham DM (38,6% entre os isseis e 34,5% nos nisseis); 51,8% tinham SM (59,4% nos isseis e 50,0% nos nisseis). A presença de zona inativa nos isseis diabéticos não foi estatisticamente significante quando comparada com os não diabéticos, porém entre os nisseis diabéticos a zona inativa estava presente em 7,5%. Houve correlação estatisticamente significante entre a SM e HVE nos isseis e nisseis. Conclusões: Distúrbios metabólicos tiveram alta prevalência em nipo-brasileiros com correlações significantes com necrose e hipertrofia pelo ECG.
- ItemAcesso aberto (Open Access)Diabetes mellitus tipo 2: fatores preditivos na população nipo-brasileira(Sociedade Brasileira de Endocrinologia e Metabologia, 2003-10-01) Nascimento, Rogéria do [UNIFESP]; Franco, Laercio Joel [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Hirai, Amélia Toyomi [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)In order to identify the main predictors for the development of type 2 diabetes mellitus (DM2) in a population with high prevalence of DM - the Japanese-Brazilians -, we evaluated 314 individuals with Japanese ancestry from Bauru, SP, aged 40 years or more, without miscegenation, in 1993 and 2000. The parameters evaluated, obtained in 1993, were sex, age, body mass index (BMI), waist and hip circumferences, fasting and 2h after 75g of glucose load glycemia, insulinemia and proinsulinemia, HOMA (function of the b cell and insulin resistance), lipid profile and blood pressure. The glycemic homeostasis evaluated in 2000 showed that individuals with impaired fasting glycemia or impaired glucose tolerance presented a higher risk for the progression to DM2 (60 and 70%, respectively) than normals (19%). The main variables involved in the progression to DM were BMI, waist circumference (only women), systolic blood pressure, fasting and 2h glycemia, and VLDL-cholesterol. These results showed the existing potential for the reduction in the incidence of DM2 in this population, because the main risk factors can be modified by interventions in lifestyle.
- ItemAcesso aberto (Open Access)Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira(Sociedade Brasileira de Endocrinologia e Metabologia, 2008-02-01) Siqueira, Antonela F. A. [UNIFESP]; Harima, Helena A. [UNIFESP]; Osiro, Katsumi [UNIFESP]; Hirai, Amélia Toyomi [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP); Japanese-Brazilian Diabetes Study GroupHigh prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged >30 years. Hypercholesterolemia was defined as serum cholesterol > 240 mg/dL, hypertriglyceridemia as values > 150 mg/dL and low-HDL-C as values <40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7±196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1- 26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total / HDL-cholesterol ratio was lower in women (4.23 ± 0.68 vs. 4.40 ± 0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health.
- ItemAcesso aberto (Open Access)Fatores associados ao consumo de frutas, verduras e legumes em Nipo-Brasileiros(Associação Brasileira de Saúde Coletiva, 2009-09-01) Palma, Raphaela Fernanda Muniz; Barbieri, Patrícia; Damião, Renata [UNIFESP]; Poletto, Juliana [UNIFESP]; Chaim, Rita; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Sartorelli, Daniela Saes; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP); Universidade Sagrado Coração; Faculdade de Saúde Pública Departamento de NutriçãoThe determination of factors associated with fruit and vegetable intake is an important tool for the development of effective intervention programs aimed at increasing the consumption of these foods. The objective of the present cross-sectional study was to identify the factors associated with the adequate consumption of fruit and vegetables (> 400g/day) among 581 adult Japanese-Brazilians, 1st and 2nd generations of immigrants, living in Bauru, SP, Brazil. Food consumption was estimated using three 24-hour recalls. On adjusted logistic regression models, higher meal frequencies were associated with a better chance of adequate daily intake of fruit and vegetables [OR (95% CI)]: [1.31 (1.05, 1.63)]. Nevertheless, individuals at the highest tertile of saturated fat intake were less likely to have adequate daily intake of these foods [0.35 (0.21, 0.60)]. A trend toward adequate intake of fruit and vegetables was found among older participants. These results suggest that more intensive intervention programs are needed among young individuals with higher saturated fat intake. Moreover, higher meal frequency might promote better adherence to the goals of daily fruit and vegetable intake.
- ItemEmbargoHiperlipidemias e fatores dietéticos: estudo transversal entre nipo-brasileiros(Universidade Federal de São Paulo (UNIFESP), 2006-12-31) Bevilacqua, Marselle Rodrigues [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)The present study had as objective to evaluate the association between hyperlipidemia and dietary patterns of Japanese-Brazilians with and without hypothyroidism from Bauru. We evaluated 1330 first- and second generation subjects of aged 30 years or more in the course of 1999 and 2000. Demographic and dietary measurement, were gotten through standardized questionnaires previously tested. Clinical examination and laboratory data were anthropometry, blood pressure, fasting and 2-h poast glucose load, lipid profile and TSH and free T4. The chi-square and the odds ratio were used to evaluate associations between hyperlipidemia with studied variables. The prevalence of hyperlipidemia was 81,5% and it was associated with smorkers, overweight, hypothyroid, hypertensive and glucose intolerants. We observed, in crude analysis, relationships with the presence of hyperlipidemia and fat saturated, oleic acid and dietary fiber from grains and cereals. After adjusting for the control variables, we observed relationships between hyperlipidemia (hypercholesterolemia and hypertriglyceridemia) with habitual intake of total fat, oleic acid, saturated fat, trans fat, carbohydrates, dietary fiber and alchool. As a conclusion, in japanese-brazilians, the hyperlipidemia, beyond classical cardiovascular risk factors, also is associated with dietary patterns.
- ItemAcesso aberto (Open Access)Hiperlipidemias e fatores dietéticos: estudo transversal entre nipo-brasileiros(Sociedade Brasileira de Endocrinologia e Metabologia, 2007-06-01) Bevilacqua, Marselle Rodrigues [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Matsumura, Luiza Kimiko [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)This study aimed at evaluating the association between hyperlipidemia and dietary patterns of Japanese Brazilians with and without hypothyroidism from Bauru, city in the State of São Paulo. We evaluated 1,330 individuals by means of demographic and dietary measurement, whom were gotten through standardized questionnaires previously tested. Clinical examination and laboratory data were anthropometry, blood pressure, fasting and 2-h glucose load, lipid profile and TSH and free T4. The chi-square and the odds ratio were used to evaluate associations between hyperlipidemia with studied variables. The prevalence of hyperlipidemia was 81.5% and it was associated with smokers, overweight, hypothyroid, hypertensive and glucose intolerants. We observed, in crude analysis, relationships with the presence of hyperlipidemia and fat saturated, oleic acid and dietary fiber from grains and cereals. After adjusting for the control variables, we observed relationships between hyperlipidemia (hypercholesterolemia and hypertriglyceridemia) with habitual intake of total fat, oleic acid, saturated fat, trans fat, dietary fiber and alcohol. As a conclusion, changes in the style of life, particularly in the dietary habits, can improve lipidic profile and that lipids intake can be a risk factor for hyperlipidemia. Prospectives studies will help test the hypothesis in Japanese Brazilians from Bauru.
- ItemAcesso aberto (Open Access)Prevalência de hiperuricemia e fatores nutricionais associados: um estudo transversal com nipo-brasileiros do município de Bauru(Universidade Federal de São Paulo (UNIFESP), 2009-03-25) Poletto, Juliana [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)This study aimed to estimate the prevalence of hiperuricemia among Japanese-Brazilians living in Bauru city (Sao Paulo) as well to verify the existence of associations between this disease and nutritional factors. METHODS: Data were obtained from 1,330 individuals using previously tested questionnaires (demographic, health history and food intake data), physical examination (health status and blood pressure) and laboratory procedures (uric acid, creatinine, fasting and 2 h glucose, total cholesterol and fractions). Chi-square and prevalence ratios were used to evaluate associations between hyperuricemia and nutritional variables. RESULTS: The prevalence of hyperuricemia was 35.3% and it occurred more frequently among smoker individuals, men subjects, aged . 55 years, with overweight or obesity, central obesity, glucose intolerance, hypercholesterolemia, hypertrigliceridemia, using specific drugs and with creatinine levels >1.4 mg/dL. We found in the crude analysis that hiperuricemia was associated with total calories, total fat, saturated, alcohol, red and processed meats, milk and dairy products, and citric fruits intake. After control variables adjustment remained statistically significant the associations between hyperuricemia and body weight excess, central obesity, hypertrigliceridemia and use of specific drugs. CONCLUSION: High hiperuricemia prevalence rate was found among these Japanese-Brazilians and changes in nutritional profile including weight and body fat reductions may help to minimize the occurrence of this disease in that community.
- ItemAcesso aberto (Open Access)Should body mass index be adjusted for relative sitting height in cross-sectional studies of chronic diseases in Japanese-Brazilians?(Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2006-08-01) Ribeiro, Adriana Bouças [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Andreoni, Solange [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)The current article aimed to verify the degree of agreement in classification of nutritional status according to body mass index (BMI) and corrected body mass index (BMIc). Data were used from a cross-sectional study of Japanese-Brazilians. Statistical analysis provided prevalence rates for chronic diseases, kappa statistic, and Pearson's linear correlation coefficient. Some 5.9% of Japanese-Brazilians were discordant according to the BMI and BMIc classifications. The weighted kappa statistic (0.94; p = 0.000) indicated good agreement between the classifications. Similar prevalence rates for chronic diseases were obtained for individuals with excess weight classified by these two indices. Similar Pearson's linear correlation coefficients were obtained for these indices and waist circumference and body fat measurements. The results suggest that BMI correction for relative sitting height is probably unnecessary for these individuals.