A review on orally disintegrating films (ODFs) made from natural polymers such as pullulan, maltodextrin, starch, and others

dc.citation.volumev. 178pt_BR
dc.contributor.authorPacheco, Murilo Santos [UNIFESP]
dc.contributor.authorBarbieri, Douglas [UNIFESP]
dc.contributor.authorSilva, Classius Ferreira da [UNIFESP]
dc.contributor.authorMoraes, Mariana Agostini de [UNIFESP]
dc.contributor.authorLatteshttp://lattes.cnpq.br/3144315657723917pt_BR
dc.date.accessioned2021-03-09T20:36:46Z
dc.date.available2021-03-09T20:36:46Z
dc.date.issued2021-05-01
dc.description.abstractIn recent years, orally disintegrating films (ODFs) have been studied as alternative ways for drug administration. They can easily be applied into the mouth and quickly disintegrate, releasing the drug with no need of water ingestion and enabling absorption through the oral mucosa. The ODFs matrices are typically composed of hydrophilic polymers, in which the natural polymers are highlighted since they are polymers extracted from natural sources, non-toxic, biocompatible, biodegradable, and have favorable properties for this application. Besides that, natural polymers such as polysaccharides and proteins can be applied either alone or blended with other synthetic, semi-synthetic, or natural polymers to achieve better mechanical and mucoadhesive properties and fast disintegration. In this review, we analyzed ODFs developed using natural polymers or blends involving natural polymers, such as maltodextrin, pullulan, starch, gelatin, collagen, alginate, chitosan, pectin, and others, to overview the recent publications and discuss how natural polymers can influence ODFs properties.pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipIDFAPESP: 2018/25656-0pt_BR
dc.description.sponsorshipIDCNPq: 308994/2017-5pt_BR
dc.format.extent504-513pt_BR
dc.identifierhttps://doi.org/10.1016/j.ijbiomac.2021.02.180pt_BR
dc.identifier.citationPACHECO, Murilo Santos; BARBIERI, Douglas; SILVA, Classius Ferreira da; MORAES, Mariana Agostini de. A review on orally disintegrating films (ODFs) made from natural polymers such as pullulan, maltodextrin, starch, and others. International Journal of Biological Macromolecules, v. 78, p. 504-513, 2021. ISSN 0141-8130. DOI: 10.1016/j.ijbiomac.2021.02.180pt_BR
dc.identifier.doi10.1016/j.ijbiomac.2021.02.180pt_BR
dc.identifier.issn0141-8130pt_BR
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/60294
dc.languageengpt_BR
dc.publisherElsevierpt_BR
dc.relation.ispartofInternational Journal of Biological Macromoleculespt_BR
dc.rightsAcesso restritopt_BR
dc.subjectOrodispersible filmpt_BR
dc.subjectFast dissolving filmpt_BR
dc.subjectOral strippt_BR
dc.subjectCastingpt_BR
dc.subjectDisintegration timept_BR
dc.subjectFilm-forming agentpt_BR
dc.titleA review on orally disintegrating films (ODFs) made from natural polymers such as pullulan, maltodextrin, starch, and otherspt_BR
dc.typeArtigopt_BR
unifesp.assessoresproreitoriasPró-reitoria de Pós-graduação e Pesquisapt_BR
unifesp.campusInstituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF)pt_BR
unifesp.departamentoEngenharia Químicapt_BR
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