Paradoxical sleep deprivation potentiates amphetamine-induced behavioural sensitization by increasing its conditioned component

Página do item simplificado
dc.contributor.authorFrussa-Filho, Roberto [UNIFESP]
dc.contributor.authorGonçalves, Michele Themis Moraes [UNIFESP]
dc.contributor.authorAndersen, Monica Levy [UNIFESP]
dc.contributor.authorAraujo, Nilza Pereira de [UNIFESP]
dc.contributor.authorChinen, Cibele Cristina [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:37:06Z
dc.date.available2016-01-24T12:37:06Z
dc.date.issued2004-04-02
dc.description.abstractThe effects of paradoxical sleep deprivation (PSD-48 h) on the conditioned and unconditioned components of behavioural sensitization to amphetamine (two injections of 2.0 mg/kg, separated by 7 days) were studied using locomotion frequency of mice observed in an open-field as experimental parameter. Behavioural sensitization only occurred in PS deprived mice that were exposed to the open-field after the first amphetamine injection. the possible involvement of PSD in the development of a Pavlovian association between the stimulant effect of amphetamine and environmental as well as interoceptive drug cues is discussed. (C) 2004 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Farmacol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Psicobiol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Farmacol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Psicobiol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt
dc.description.sponsorshipAssociação Fundo de Incentivo à Psicofarmacologia (AFIP)pt
dc.description.sponsorshipIDFAPESP: 98/13611-6pt
dc.description.sponsorshipIDFAPESP/CEPID: 98/14303-3pt
dc.format.extent188-193
dc.identifierhttps://dx.doi.org/10.1016/j.brainres.2003.11.050
dc.identifier.citationBrain Research. Amsterdam: Elsevier B.V., v. 1003, n. 1-2, p. 188-193, 2004.
dc.identifier.doi10.1016/j.brainres.2003.11.050
dc.identifier.issn0006-8993
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/27706
dc.identifier.wosWOS:000220830000023
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofBrain Research
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectParadoxical sleep deprivationen
dc.subjectBehavioral sensitizationen
dc.subjectAmphetamineen
dc.subjectOpen-field behavioren
dc.subjectConditioningen
dc.titleParadoxical sleep deprivation potentiates amphetamine-induced behavioural sensitization by increasing its conditioned componenten
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos