Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis

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2006-02-01
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Artigo
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Resumo
Three HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes. This finding raises the question of potential mechanisms involved in the activation or loss of T-cells in disseminated tuberculosis.
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Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 10, n. 1, p. 59-61, 2006.
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