Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis

Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis

Autor Rodrigues, Denise do Socorro da Silva Autor UNIFESP Google Scholar
Salomão, Reinaldo Autor UNIFESP Google Scholar
Kallas, Esper Georges Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Three HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes. This finding raises the question of potential mechanisms involved in the activation or loss of T-cells in disseminated tuberculosis.
Palavra-chave Mycobacterium tuberculosis
disseminated tuberculosis
lymphocyte
cellular activation
Idioma Inglês
Data de publicação 2006-02-01
Publicado em Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 10, n. 1, p. 59-61, 2006.
ISSN 1413-8670 (Sherpa/Romeo)
Publicador Brazilian Society of Infectious Diseases
Extensão 59-61
Fonte http://dx.doi.org/10.1590/S1413-86702006000100012
Direito de acesso Acesso aberto Open Access
Tipo Artigo
SciELO S1413-86702006000100012 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/2920

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