Eficácia da enzimas Lipolíticas Fosfatidilcolina e Ácido Deóxicólico na redução de gordura localizada corporal: uma revisão integrativa
Data
2024-09-06
Autores
Messias, Taluana Aparecida Nascimento 
Orientadores
Aveiro, Mariana Chaves
Tipo
Trabalho de conclusão de curso
Título da Revista
ISSN da Revista
Título de Volume
Resumo
A supervalorização do corpo nos dias atuais, faz com que as mulheres busquem métodos e alternativas para reduzir a gordura localizada e para melhorar o contorno corporal. A aplicação de injetáveis com substâncias lipolíticas, denominada intradermoterapia vem crescendo, devido a sua facilidade e baixo custo para o tratamento de gordura localizada. Pistor, um médico francês, criou a técnica de intradermoterapia, que consiste na em injeções com fármacos lipolíticos altamente diluídos (Fosfatidilcolina e Ácido Deoxicólico), introduzidas no tecido subcutâneo para o tratamento de gordura localizada. Na intradermoterapia, os agentes lipolíticos induzem a lipólise, reduzindo medidas. Objetivos: Este trabalho teve como objetivo sintetizar as evidências sobre a eficácia das enzimas lipolíticas fosfatidilcolina e ácido deoxicólico na redução de gordura localizada corporal de mulheres adultas. Métodos: Foi realizada uma revisão integrativa da literatura de artigos nos idiomas Português, inglês e espanhol sobre a efetividade dos agentes lipolíticos: fosfatidilcolina e ácido deoxicólico. As buscas foram realizadas nas bases de dados PUBMED E Lilacs/Biblioteca Virtual em Saúde. Resultado: Foram encontrados 49 artigos, 35 não se encaixavam nos critérios de inclusão, 3 artigos duplicados na base de pesquisas, 2 artigos não estavam disponíveis em textos completos, sendo selecionados 9 artigos. Conclusão: A intradermoterapia tem um efeito satisfatório na redução de medidas, com os agentes lipolíticos fosfatidilcolina e ácido deoxicólico, entretanto temos uma escassez de estudos sobre o assunto.
Due to the overvaluation of the body nowadays, women have been looking for methods and alternatives to reduce localized fat, to improve their body contour. The application of injectables with lipolytic substances, called intradermotherapy, has been growing due to its ease and low cost for treating localized fat. Pistor, a French doctor, created the intradermotherapy technique, which consists of injections with highly diluted lipolytic drugs (Phosphatidylcholine and Deoxycholic Acid), introduced into the subcutaneous tissue to treat localized fat. Localized fat is a cellular disorder in the metabolism of adipocytes with their excess growth, in specific places on the body, such as the abdomen, thighs, back and arms. In intradermotherapy, lipolytic agents induce lipolysis, reducing measurements. Objectives: the objective of this work was to carry out a literature review to synthesize the evidence on the effectiveness of the lipolytic enzymes phosphatidylcholine and deoxycholic acid in reducing localized body fat in adult women. Methods: An integrative literature review of articles in Portuguese, English and Spanish was carried out on the effectiveness of lipolytic agents: phosphatidylcholine and deoxycholic acid, searches were carried out in the PUBMED and Lilacs/Biblioteca Virtual em Saúde. Result: There were 49 articles were found, 35 did not meet the inclusion criteria, 2 articles were not available in full texts, 9 articles were selected. Studies demonstrate that lipolytic agents: phosphatidylcholine and deoxycholic acid are effective in local fat lipolysis, resulting in reduced measurements. Conclusion: Intradermotherapy has a satisfactory effect on reducing measurements, with lipolytic agents: phosphatidylcholine and deoxycholic acid, however there is a lack of studies on the subject.
Due to the overvaluation of the body nowadays, women have been looking for methods and alternatives to reduce localized fat, to improve their body contour. The application of injectables with lipolytic substances, called intradermotherapy, has been growing due to its ease and low cost for treating localized fat. Pistor, a French doctor, created the intradermotherapy technique, which consists of injections with highly diluted lipolytic drugs (Phosphatidylcholine and Deoxycholic Acid), introduced into the subcutaneous tissue to treat localized fat. Localized fat is a cellular disorder in the metabolism of adipocytes with their excess growth, in specific places on the body, such as the abdomen, thighs, back and arms. In intradermotherapy, lipolytic agents induce lipolysis, reducing measurements. Objectives: the objective of this work was to carry out a literature review to synthesize the evidence on the effectiveness of the lipolytic enzymes phosphatidylcholine and deoxycholic acid in reducing localized body fat in adult women. Methods: An integrative literature review of articles in Portuguese, English and Spanish was carried out on the effectiveness of lipolytic agents: phosphatidylcholine and deoxycholic acid, searches were carried out in the PUBMED and Lilacs/Biblioteca Virtual em Saúde. Result: There were 49 articles were found, 35 did not meet the inclusion criteria, 2 articles were not available in full texts, 9 articles were selected. Studies demonstrate that lipolytic agents: phosphatidylcholine and deoxycholic acid are effective in local fat lipolysis, resulting in reduced measurements. Conclusion: Intradermotherapy has a satisfactory effect on reducing measurements, with lipolytic agents: phosphatidylcholine and deoxycholic acid, however there is a lack of studies on the subject.
Descrição
Citação
MESSIAS, Taluana Aparecida Nascimento. Eficácia da enzimas Lipolíticas Fosfatidilcolina e Ácido Deóxicólico na redução de gordura localizada corporal: uma revisão integrativa. 2024. 45 f. Trabalho de conclusão de curso (Graduação em Fisioterapia) - Universidade Federal de São Paulo, Instituto de Saúde e Sociedade, Santos, 2024.