Capacidade do exercício e comportamento da saturação de pulso de oxigênio em pacientes com COVID-19: evolução em 1 ano
Data
2024
Autores
Nozaki, Deise Garcia 
Orientadores
Sperandio, Priscila Cristina de Abreu
Tipo
Dissertação de mestrado
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Pacientes acometidos pela Covid19 apresentam comprometimento em vários sistemas do corpo, com prejuízo em diversas funções e atividades básicas rotineiras, fato que pode impactar diretamente na qualidade de vida. O diagnóstico clínico e a adoção de intervenções terapêuticas precoces se fazem necessárias. Objetivo: Avaliar ao longo de um ano, 90 dias, 180 dias e 360 dias dias após o início dos sintomas, a capacidade funcional e a saturação periférica de oxigênio (SpO2) pelo teste do degrau em 4 minutos, em pacientes que foram hospitalizados por Covid-19. Nossa hipótese é que a capacidade funcional e a saturação de pulso de oxigênio estarão melhores a cada avaliação. Métodos: Estudo de coorte, que foi realizado nas unidades de internação por Covid-19 e também no ambulatório pós-Covid-19 por um período de um ano. Foram avaliados dados demográficos, principais sintomas no incio do pós covid-19, Índice de massa corporal e sintomas em 03 visitas e as variáveis do teste do degrau de 4 minutos que são: SpO2, FC, escala de Borg e TD4 de 37 pacientes. Resultados: Os dados demográficos indicam idade média de 56 anos, sendo 62% do sexo masculino, 65% de cor Branca com 26 dias de internação, sendo 13 dias em UTI. Com relação aos sintomas 84% apresentou desconforto respiratório com dispneia, tosse, estado febril e/ou mialgia. Observou se diminuição do IMC e dos sintomas dispneia, tosse e mialgia nas visitas 2 e 3. Houve aumento da fadiga, principalmente na segunda visita. Não houve correlação entre as variáveis tempo de internação, SpO2, dispneia, fadiga e número de degraus avaliados em todas as visitas (90 dias; 180 dias; 360 dias, exceto de 360 dias em que houve correlação fraca e negativa entre dispneia e número de degraus (R=-34 p= 0,04). Conclusões: Houve melhora na capacidade funcional em pacientes acometidos pela covid-19 ao longo de um ano, com diminuição da dispneía, mialgia e do Indíce de Massa Corporal. A saturação periférica de oxigênio se manteve leve a moderadamente anormal. Não houve correlação entre os dias de internação em unidade de terapia intensiva (UTI) e/ou enfermaria, número de degraus, saturação de pulso de oxigênio, dispneia e fadiga de membros inferiores (MMII) nas visitas de 90 e 180 dias.
Patients affected by Covid19 present impairment in several body systems, with impairment in several functions and basic routine activities, a fact that can directly impact their quality of life. Clinical diagnosis and adoption of early therapeutic interventions are necessary Objective: To evaluate, over one year, 90 (V1), 180 (V2) and 360 (V3) days after the onset of symptoms, functional capacity and peripheral oxygen saturation (SpO2) using the 4-minute step test, in patients who were hospitalized for Covid-19. Our hypothesis is that functional capacity and pulse oxygen saturation will be better with each assessment. Methods: Cohort study, which was carried out in the Covid19 inpatient units and also in the post-Covid19 outpatient clinic for a period of one year. Demographic data, main symptoms at the beginning of post-covid19, body mass index and symptoms in 3 visits and the variables of the 4-minute step test were evaluated, which are: SpO2, HR, Borg scale and TD4 of 37 patients. Results: Demographic data indicate an average age of 56 years, 62% male, 65% White with 26 days of hospitalization, 13 days in the ICU. Regarding symptoms, 84% had respiratory discomfort with dyspnea, cough, fever and/or myalgia. A decrease in BMI and symptoms of dyspnea, cough and myalgia was observed on visits 2 and 3. There was an increase in fatigue, especially on the second visit. There was no correlation between the variables length of stay, SpO2, dyspnea, fatigue and number of steps assessed at all visits (90 days; 180 days; 360 days), except at 360 days where there was a weak and negative correlation between dyspnea and number of steps (R =-34 p= 0.04). Conclusions: There was an improvement in function capacity in patients affected by Covid-19 over the course of a year, with a decrease in dyspnea, myalgia and Body Mass Index. Peripheral oxygen saturation remained mild to moderately abnormal. There was no correlation between days spent in the intensive care unit (ICU) and/or ward, number of steps, oxygen pulse saturation, dyspnea and lower limb fatigue (LL) on visits 1 and 2.
Patients affected by Covid19 present impairment in several body systems, with impairment in several functions and basic routine activities, a fact that can directly impact their quality of life. Clinical diagnosis and adoption of early therapeutic interventions are necessary Objective: To evaluate, over one year, 90 (V1), 180 (V2) and 360 (V3) days after the onset of symptoms, functional capacity and peripheral oxygen saturation (SpO2) using the 4-minute step test, in patients who were hospitalized for Covid-19. Our hypothesis is that functional capacity and pulse oxygen saturation will be better with each assessment. Methods: Cohort study, which was carried out in the Covid19 inpatient units and also in the post-Covid19 outpatient clinic for a period of one year. Demographic data, main symptoms at the beginning of post-covid19, body mass index and symptoms in 3 visits and the variables of the 4-minute step test were evaluated, which are: SpO2, HR, Borg scale and TD4 of 37 patients. Results: Demographic data indicate an average age of 56 years, 62% male, 65% White with 26 days of hospitalization, 13 days in the ICU. Regarding symptoms, 84% had respiratory discomfort with dyspnea, cough, fever and/or myalgia. A decrease in BMI and symptoms of dyspnea, cough and myalgia was observed on visits 2 and 3. There was an increase in fatigue, especially on the second visit. There was no correlation between the variables length of stay, SpO2, dyspnea, fatigue and number of steps assessed at all visits (90 days; 180 days; 360 days), except at 360 days where there was a weak and negative correlation between dyspnea and number of steps (R =-34 p= 0.04). Conclusions: There was an improvement in function capacity in patients affected by Covid-19 over the course of a year, with a decrease in dyspnea, myalgia and Body Mass Index. Peripheral oxygen saturation remained mild to moderately abnormal. There was no correlation between days spent in the intensive care unit (ICU) and/or ward, number of steps, oxygen pulse saturation, dyspnea and lower limb fatigue (LL) on visits 1 and 2.
Descrição
Citação
NOZAKI, Deise Garcia. Capacidade do exercício e comportamento da saturação de pulso de oxigênio em pacientes com COVID-19: evolução em 1 ano. 2024. 65 f. Dissertação (Mestrado em Pneumologia) - Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP). São Paulo, 2024.