Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning

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dc.citation.volume20
dc.contributor.authorVida, Talita Almeida
dc.contributor.authorMotta, Adriana Cristina
dc.contributor.authorSantos, Arnaldo Rodrigues, Jr.
dc.contributor.authorCardoso, Guinea Brasil Camargo
dc.contributor.authorBrito, Crystopher Cardoso de [UNIFESP]
dc.contributor.authorZavaglia, Cecília Amélia de Carvalho
dc.coverageSao Carlos
dc.date.accessioned2020-07-17T14:03:18Z
dc.date.available2020-07-17T14:03:18Z
dc.date.issued2017
dc.description.abstractRotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In opposite, electrospinning technique needs the presence of an external electric field to create fiber from the polymeric jet solution. This article investigates both processes using two different biocompatible polymers: Poly(L-lactic acid) (PLLA) and Poly(e-caprolactone) (PCL). Samples were characterized by scanning electron microscopy, thermogravimetric analysis, differential scanning calorimeter, and Fourier-transform infrared spectroscopy. Morphological observations showed the efficiency of both techniques in obtaining nanofibers. Thermal analyses of data indicate immiscible property of different blends and the total solvent evaporation. In vitro cytocompatibility test showed that RJS and electrospinning samples exhibited good cytocompatibility. Based on these results, it may be concluded that the fibers obtained with both technologies are non-cytotoxicity and with good biocompatibility, and might be suitable for applications as scaffold for cell growth.en
dc.description.affiliationUniv Estadual Campinas, Fac Engn Mecan, Campinas, SP, Brazil
dc.description.affiliationPontificia Univ Catolica, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed ABC, Ctr Ciencias Nat & Humanas, Santo Andre, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Ciencias Mar, Santos, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Ciencias Mar, Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipBiofabris-INCT
dc.description.sponsorshipBiomaterials Laboratory PUC/SP Sorocaba
dc.description.sponsorshipIDFAPESP: 2013/19372-0
dc.format.extent910-916
dc.identifierhttps://dx.doi.org/10.1590/1980-5373-MR-2016-0969
dc.identifier.citationMaterials Research-Ibero-American Journal Of Materials. Sao Carlos, v. 20, p. 910-916, 2017.
dc.identifier.doi10.1590/1980-5373-MR-2016-0969
dc.identifier.fileS1516-14392017000800910.pdf
dc.identifier.issn1516-1439
dc.identifier.scieloS1516-14392017000800910
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55288
dc.identifier.wosWOS:000430187600131
dc.language.isoeng
dc.publisherUniv Fed Sao Carlos, Dept Engenharia Materials
dc.relation.ispartofMaterials Research-Ibero-American Journal Of Materials
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectRotary jet spinningen
dc.subjectElectrospinningen
dc.subjectBlenden
dc.subjectNanofibersen
dc.subjectBiomaterialsen
dc.titleFibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinningen
dc.typeinfo:eu-repo/semantics/article
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