Efeitos da quarentena durante a pandemia de COVID-19 no padrão do sono em uma população com narcolepsia

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dc.contributor.advisorCoelho, Fernando Morgadinho Santos [UNIFESP]
dc.contributor.advisor-coFrange, Cristina Mattos Pereira
dc.contributor.advisor-coLatteshttp://lattes.cnpq.br/5507825991578153pt_BR
dc.contributor.advisorLatteshttp://lattes.cnpq.br/4520146294812879pt_BR
dc.contributor.authorAguilar, Ana Carolina Rodrigues [UNIFESP]
dc.contributor.authorLatteshttp://lattes.cnpq.br/7290211396937157pt_BR
dc.coverage.spatialSão Paulopt_BR
dc.date.accessioned2022-06-30T13:28:51Z
dc.date.available2022-06-30T13:28:51Z
dc.date.issued2021-09-10
dc.description.abstractStudy Objectives: To the best of our knowledge, there has not as yet been any study on the effects of the COVID-19 pandemic on patients with narcolepsy; in particular in relation to its impact on sleep schedules, symptoms, the need for medication, work, income, and quality of life. This study therefore aimed to explore these factors and their possible influence on sleep, circadian timing and narcolepsy symptoms during the pandemic. Methods: Patients with narcolepsy who had been in quarantine for at least three months completed an online questionnaire. Questions targeted the conditions of the quarantine, sleep-related behaviors, and factors known to affect sleep and circadian rhythms (work status, income, appetite, narcolepsy symptoms, and medication), as well as the quality of life during the quarantine period. Results: The routines of the participants had been altered by quarantine, with changes in their place of work, and an increase in narcolepsy symptoms such as cataplexy, sleep paralysis, hallucinations, nocturnal awakenings, and sleepiness. Sleep and wake times changed, resulting in altered sleep patterns in the majority of the sample. No association between changes in the place of work and narcolepsy symptoms was found. Regarding medication, the participants used fewer antidepressant pills but took more stimulants. Appetite was increased and self-reported quality of life decreased during the period. Conclusions: During the quarantine the patients with narcolepsy reported worsening of narcolepsy symptoms and increased use of stimulants, furthermore was observed changes in their bedtime and waking-up schedules, suggesting a tendency to circadian misalignment. In Brazil, the effects of the COVID-19 outbreak have gone beyond the direct action of the virus, because of the collateral damage it has caused in respect of unemployment and financial hardship. These impacts have been amplified in Brazil because of the level of social inequality found in the country, and they have particularly affected vulnerable patients with rare diseases, such as the narcolepsy population.pt_BR
dc.format.extent85 f.pt_BR
dc.identifier.citationAGUILAR, Ana Carolina Rodrigues. Efeitos da quarentena durante a pandemia de COVID-19 no padrão do sono em uma população com narcolepsia. São Paulo, 2021. 85 f. Dissertação (Mestrado em Psicobiologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, 2021.pt_BR
dc.identifier.urihttps://hdl.handle.net/11600/64025
dc.languageporpt_BR
dc.publisherUniversidade Federal de São Paulopt_BR
dc.rightsAcesso abertopt_BR
dc.subjectSonopt_BR
dc.subjectNarcolepsiapt_BR
dc.subjectRitmo circadianopt_BR
dc.subjectQualidade de vidapt_BR
dc.subjectCovid-19pt_BR
dc.subjectQuarentenapt_BR
dc.subjectPandemiapt_BR
dc.subjectIsolamento socialpt_BR
dc.titleEfeitos da quarentena durante a pandemia de COVID-19 no padrão do sono em uma população com narcolepsiapt_BR
dc.title.alternativeThe influence of pandemic era of COVID-19 in narcolepsy patientsen
dc.typeDissertação de mestradopt_BR
unifesp.campusEscola Paulista de Medicina (EPM)pt_BR
unifesp.graduateProgramPsicobiologiapt_BR
unifesp.knowledgeAreaMedicina do Sonopt_BR
unifesp.researchAreaPesquisa clínica em medicina do sono, ênfase em sonolência excessiva diurnapt_BR
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