The impact of lupus erythematosus cutaneous on the quality of life: the Brazilian-Portuguese version of DLQI

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dc.contributor.authorFerraz, L. B.
dc.contributor.authorAlmeida, F. A.
dc.contributor.authorVasconcellos, M. R.
dc.contributor.authorFaccina, A. S.
dc.contributor.authorCiconelli, R. M.
dc.contributor.authorFerraz, M. B.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:41:03Z
dc.date.available2016-01-24T12:41:03Z
dc.date.issued2006-04-01
dc.description.abstractObjective: To translate into Brazilian-Portuguese, culturally adapt and validate the DLQI. Patients and Methods: the DLQI was translated into Brazilian-Portuguese and cultural adaptation was performed following the methodology proposed by Falcao. Inter-observer reliability and validity were assessed. Seventy-one patients with lupus erythematosus with cutaneous lesions selected from the outpatient dermatology clinic had their quality of life assessed by DLQI and SF-36. the validity of the Brazilian-Portuguese version of the DLQI was evaluated by the correlation of DLQI scores with SF-36 component scores and other outcome measures. Results: in the translation and cultural adaptation process the basic structure of DLQI was kept. Very few questions have very slightly modifications. of the 71 patients, 83% were women and the median (SD) age was 38 (12) years. the patients had a mean (SD) disease duration of 8(6) years. There were 46 patients with active cutaneous lesions and 37 patients with alopecia. the DLQI inter-observer reliability coefficient was 0.96 (p < 0.001). the DLQI mean (SD) score was 6.5 (5.6) and most of the SF-36 domains were between 60 and 70. the domains that had the lowest scores were 'Cygeneral health' (62) and 'Cymental health' (62). the Pearson correlation coefficient between DLQI and each SF-36 component score were highly statistically significant (p < 0.001), despite of being only moderate. As expected there was no correlation between DLQI or each one of the SF-36 components and age, disease duration or number of ACR criteria. Patients with active cutaneous lesions presented statistically significant lower scores of DLQI and SF-36 when compared to patients without active cutaneous lesions. Patients with alopecia presented a statistically significant lower score in DLQI when compared to patients without alopecia. Conclusions: the results suggest that the Brazilian-Portuguese version of the DLQI is a reliable and valid outcome measure to be used in LE clinical studies.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Dermatol, BR-040123 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Div Rheumatol, Dept Med, BR-040123 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Dermatol, BR-040123 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Div Rheumatol, Dept Med, BR-040123 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent565-570
dc.identifierhttp://dx.doi.org/10.1007/s11136-005-2638-9
dc.identifier.citationQuality of Life Research. Dordrecht: Springer, v. 15, n. 3, p. 565-570, 2006.
dc.identifier.doi10.1007/s11136-005-2638-9
dc.identifier.issn0962-9343
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/28809
dc.identifier.wosWOS:000236100300026
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofQuality of Life Research
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.subjectlupusen
dc.subjectoutcome measureen
dc.subjectquality of lifeen
dc.subjectquestionnaireen
dc.titleThe impact of lupus erythematosus cutaneous on the quality of life: the Brazilian-Portuguese version of DLQIen
dc.typeinfo:eu-repo/semantics/article
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