The impact of lupus erythematosus cutaneous on the quality of life: the Brazilian-Portuguese version of DLQI
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2006-04-01
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Artigo
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Objective: To translate into Brazilian-Portuguese, culturally adapt and validate the DLQI. Patients and Methods: the DLQI was translated into Brazilian-Portuguese and cultural adaptation was performed following the methodology proposed by Falcao. Inter-observer reliability and validity were assessed. Seventy-one patients with lupus erythematosus with cutaneous lesions selected from the outpatient dermatology clinic had their quality of life assessed by DLQI and SF-36. the validity of the Brazilian-Portuguese version of the DLQI was evaluated by the correlation of DLQI scores with SF-36 component scores and other outcome measures. Results: in the translation and cultural adaptation process the basic structure of DLQI was kept. Very few questions have very slightly modifications. of the 71 patients, 83% were women and the median (SD) age was 38 (12) years. the patients had a mean (SD) disease duration of 8(6) years. There were 46 patients with active cutaneous lesions and 37 patients with alopecia. the DLQI inter-observer reliability coefficient was 0.96 (p < 0.001). the DLQI mean (SD) score was 6.5 (5.6) and most of the SF-36 domains were between 60 and 70. the domains that had the lowest scores were 'Cygeneral health' (62) and 'Cymental health' (62). the Pearson correlation coefficient between DLQI and each SF-36 component score were highly statistically significant (p < 0.001), despite of being only moderate. As expected there was no correlation between DLQI or each one of the SF-36 components and age, disease duration or number of ACR criteria. Patients with active cutaneous lesions presented statistically significant lower scores of DLQI and SF-36 when compared to patients without active cutaneous lesions. Patients with alopecia presented a statistically significant lower score in DLQI when compared to patients without alopecia. Conclusions: the results suggest that the Brazilian-Portuguese version of the DLQI is a reliable and valid outcome measure to be used in LE clinical studies.
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Quality of Life Research. Dordrecht: Springer, v. 15, n. 3, p. 565-570, 2006.