Ossificação do ligamento estilo-hióideo : uma causa comum de otalgia em mulheres Turner
Arquivos
Data
2018-05-24
Autores
Rossinol, Vinicius Loures 
Orientadores
Silva, Magnus Regios Dias da
Tipo
Dissertação de mestrado
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Otalgia é uma queixa bem documentada em mulheres que sofrem de síndrome de Turner (ST). Nós hipotetizamos que, com base em um caso de índice de TS com uma longa história de dor de ouvido diagnosticada com calcificação de ligamento estillo-hióideo (CLS), conhecida por síndrome de Eagle (SE), a CLS seria comum na população com ST frequentemente tratada como otite. Este estudo teve como objetivo verificar se SE é uma das causas da otalgia em ST. MÉTODOS: analisamos 96 pacientes com ST consecutivas e 55 mulheres controle (MC). Se após a avaliação de uma paciente com ST verificássemos otalgia e/ou palpação dolorosa de palatina tonsilar, sugestivo de CLS, elas eram submetidas a Rx facial ou TC de crânio 3-D para confirmar CLS. RESULTADOS: Trinta e quatro pacientes com ST (35%) apresentaram quadro clínico de SE e 27 (28,1%) foram confirmadas radiologicamente. Dentre estas, 14 (51,9%) foram tratadas como otite recorrente devido à otalgia. Onze das pacientes com ST e SE (26,1%) tinham menos de 21 anos de idade. Não houve associação entre o diagnóstico de SE e o cariótipo, idade, índice de massa corporal e duração do uso de hormônio de crescimento. Dez mulheres controles (18,2%) queixaram-se de sintomas de SE; no entanto, apenas 4 (7,3%) confirmaram o diagnóstico de SLC (controles vs TS, p <0,01) radiologicamente e nenhum delas tinha menos de 21 anos. SE ocorreu mais em idades mais jovens na ST do que entre controles (p <0,002). CONCLUSÃO: SE é mais prevalente na ST do que nos controles, e esta ocorre em idades mais jovens. A SE deve ser avaliada como morbidade comum na ST em qualquer idade, especialmente durante a infância, como diagnóstico diferencial ao avaliar a otalgia.
Otalgia is a well-documented occurrence in women suffering from Turner Syndrome (TS). We hypothesized that, based on an index case of TS with a long-standing history of ear pain diagnosed with stylohyoid ligament calcification (SLC), so-called Eagle Syndrome (ES), SLC would be common in TS population frequently treated as otitis. This study aimed at verifying if ES is one of the causes of otalgia in TS. METHODS: We analyzed 96 consecutive TS patients and 55 control women (CW). If at evaluation a TS complained about otalgia and/or painful palpation of tonsillar palatine, suggestive of SLC, they underwent facial Rx or 3-D Cranial CT to rule out SLC. RESULTS: Thirty-four TS patients (35%) had clinical picture of ES, and 27 (28.1 %) radiologically confirmed; out of these, 14 (51.9%) had been treated as recurrent otitis due to otalgia. Eleven out of the TS with ES (26.1%) were below age 21. There was no association between the diagnosis of ES and karyotype, age, body mass index, and duration of receiving growth hormone. Ten CW (18.2%) complained about symptoms of ES; however, only 4 (7.3%) confirmed the diagnosis of SLC (CW vs. TS, p<0.01), and none of them were below 21yo. ES occurred more in younger ages in TS than controls (p< 0.002). CONCLUSION: ES is more prevalent in TS than in controls, and it occurs at younger ages. ES must be assessed as a common comorbidity of TS in any age, especially during childhood, as differential diagnosis when evaluating otalgia.
Otalgia is a well-documented occurrence in women suffering from Turner Syndrome (TS). We hypothesized that, based on an index case of TS with a long-standing history of ear pain diagnosed with stylohyoid ligament calcification (SLC), so-called Eagle Syndrome (ES), SLC would be common in TS population frequently treated as otitis. This study aimed at verifying if ES is one of the causes of otalgia in TS. METHODS: We analyzed 96 consecutive TS patients and 55 control women (CW). If at evaluation a TS complained about otalgia and/or painful palpation of tonsillar palatine, suggestive of SLC, they underwent facial Rx or 3-D Cranial CT to rule out SLC. RESULTS: Thirty-four TS patients (35%) had clinical picture of ES, and 27 (28.1 %) radiologically confirmed; out of these, 14 (51.9%) had been treated as recurrent otitis due to otalgia. Eleven out of the TS with ES (26.1%) were below age 21. There was no association between the diagnosis of ES and karyotype, age, body mass index, and duration of receiving growth hormone. Ten CW (18.2%) complained about symptoms of ES; however, only 4 (7.3%) confirmed the diagnosis of SLC (CW vs. TS, p<0.01), and none of them were below 21yo. ES occurred more in younger ages in TS than controls (p< 0.002). CONCLUSION: ES is more prevalent in TS than in controls, and it occurs at younger ages. ES must be assessed as a common comorbidity of TS in any age, especially during childhood, as differential diagnosis when evaluating otalgia.
Descrição
Citação
ROSSINOL, Vinícius Loures. Ossificação do ligamento estilo-hióideo: uma causa comum de otalgia em mulheres Turner. São Paulo, 2017. [54] p. Dissertação (Mestrado em Medicina: endocrinologia clínica) - Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, 2017.