Macrophages and apoptosis in the stellate reticulum of the rat enamel organ

dc.contributor.authorBaratella, Liriane [UNIFESP]
dc.contributor.authorArana-Chavez, V. E.
dc.contributor.authorKatchburian, Eduardo [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniv Ponta Grossa
dc.date.accessioned2016-01-24T12:31:08Z
dc.date.available2016-01-24T12:31:08Z
dc.date.issued2000-08-01
dc.description.abstractTooth germs of upper first molars of 1, 3, and 5-d-old rats, fixed in formaldehyde, were stained for the detection of apoptosis by the TUNEL method, and by the ate-dye method for the demonstration of acid phosphatase. for conventional light and electron microscopy the specimens were fixed in glutaraldehyde-formaldehyde and embedded in glycol methacrylate and Araldite. Results showed that macrophages, present in the stellate reticulum, contained basophilic bodies and TUNEL-positive globules, i.e. apoptotic bodies, in their interior. Macrophages also possessed strong acid phosphatase activity. Electron microscopy showed the presence of large vacuoles inside the macrophages containing dense fragmented material. Taken together these results suggest that the intra-epithelial macrophages of the stellate reticulum engulf apoptotic bodies.en
dc.description.affiliationUniversidade Federal de São Paulo, Sch Med, Dept Morphol, BR-04023900 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Inst Biomed Sci, Dept Histol & Embryol, São Paulo, Brazil
dc.description.affiliationUniv Ponta Grossa, Dept Biol, Ponta Grossa, PR USA
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Sch Med, Dept Morphol, BR-04023900 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent303-306
dc.identifierhttp://dx.doi.org/10.1046/j.1469-7580.2000.19720303.x
dc.identifier.citationJournal of Anatomy. New York: Cambridge Univ Press, v. 197, p. 303-306, 2000.
dc.identifier.doi10.1046/j.1469-7580.2000.19720303.x
dc.identifier.issn0021-8782
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/26348
dc.identifier.wosWOS:000089306100015
dc.language.isoeng
dc.publisherCambridge Univ Press
dc.relation.ispartofJournal of Anatomy
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.licensehttp://journals.cambridge.org/action/displaySpecialPage?pageId=4676
dc.subjecttooth germen
dc.subjectamelogenesisen
dc.subjectodontogenesisen
dc.subjectenamelen
dc.titleMacrophages and apoptosis in the stellate reticulum of the rat enamel organen
dc.typeinfo:eu-repo/semantics/article
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