A prolactin-secreting tumor in a patient with Klinefelter's syndrome: A case report
Data
1996-04-01
Autores
Pinto, Ana Claudia AR 
Mussio, W.
Lengyel, AMJ
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
We report the case of a patient with Klinefelter's syndrome who developed a prolactin (PRL)-secreting tumor. The patient developed headaches, visual alterations and also symptoms of hypogonadism despite appropriate testosterone (T) replacement therapy, The diagnosis of hyperprolactinemia was then suspected. The laboratory findings confirmed the hypothesis, showing high levels of serum PRL. The patient was initially treated with oral bromocriptine, and afterwards with the injectable form. There was a marked decrease in PRL levels and in tumor size. Although some neoplasms, like breast carcinoma and germ cell tumors, are known to occur more frequently in patients with Klinefelter's syndrome, an association with PRL-secreting tumor has not been reported yet. In conclusion, symptoms of hypogonadism in patients with Klinefelter's syndrome receiving appropriate T replacement therapy can suggest the presence of hyperprolactinemia.
Descrição
Citação
Journal Of Endocrinological Investigation. Milano: Editrice Kurtis S R L, v. 19, n. 4, p. 248-252, 1996.