Hydrolase and sialyltransferase activities of Trypanosoma cruzi trans-sialidase towards NeuAc-alpha-2,3-Gal-beta-O-PNP
| dc.contributor.author | Harrison, J. A. | |
| dc.contributor.author | Kartha, KPR | |
| dc.contributor.author | Turnbull, W. B. | |
| dc.contributor.author | Scheuerl, S. L. | |
| dc.contributor.author | Naismith, J. H. | |
| dc.contributor.author | Schenkman, S. | |
| dc.contributor.author | Field, R. A. | |
| dc.contributor.institution | Univ St Andrews | |
| dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | |
| dc.date.accessioned | 2016-01-24T12:31:18Z | |
| dc.date.available | 2016-01-24T12:31:18Z | |
| dc.date.issued | 2001-01-22 | |
| dc.description.abstract | NeuAc-alpha -2,3-Gal-beta -O-PNP has been synthesised and its ability to act as a substrate for the hydrolase and transferase activities of Trypanosoma cruzi trans-sialidase have been investigated. the turn-over of this compound shows marked differences from the behaviour of NeuAc-MU. in addition, distinct differences in the action of T. cruzi trans-sialidase and Clostridium perfringens neuraminidase on NeuAc-alpha -2,3-Gal-beta -O-PNP were apparent. (C) 2001 Elsevier B.V. All rights reserved. | en |
| dc.description.affiliation | Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland | |
| dc.description.affiliation | Escola Paulista Med, Disc Biol Celular, BR-04023062 São Paulo, Brazil | |
| dc.description.affiliationUnifesp | Escola Paulista Med, Disc Biol Celular, BR-04023062 São Paulo, Brazil | |
| dc.description.source | Web of Science | |
| dc.format.extent | 141-144 | |
| dc.identifier | http://dx.doi.org/10.1016/S0960-894X(00)00611-9 | |
| dc.identifier.citation | Bioorganic & Medicinal Chemistry Letters. Oxford: Pergamon-Elsevier B.V., v. 11, n. 2, p. 141-144, 2001. | |
| dc.identifier.doi | 10.1016/S0960-894X(00)00611-9 | |
| dc.identifier.issn | 0960-894X | |
| dc.identifier.uri | http://repositorio.unifesp.br/handle/11600/26476 | |
| dc.identifier.wos | WOS:000166648100013 | |
| dc.language.iso | eng | |
| dc.publisher | Elsevier B.V. | |
| dc.relation.ispartof | Bioorganic & Medicinal Chemistry Letters | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.license | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
| dc.title | Hydrolase and sialyltransferase activities of Trypanosoma cruzi trans-sialidase towards NeuAc-alpha-2,3-Gal-beta-O-PNP | en |
| dc.type | info:eu-repo/semantics/article |