Aplicabilidade de compensação matemática baseada em software na mudança de posição do paciente em exames de manometria esofágica perfusional
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Data
2024
Autores
Gualberto, Daniel Mello Moraes [UNIFESP]
Orientadores
Herbella Fernandes, Fernando Augusto Mardiros [UNIFESP]
Tipo
Dissertação de mestrado
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Objetivo: Validar um método de compensação matemática baseada em software
das interferências causadas pela mudança de posição do paciente em exames de
manometria esofágica perfusional. Métodos: O trabalho foi realizado em quatro
etapas: a) modelagem física e matemática, b) implementação em software, c) testes
ex-vivo e d) testes in-vivo. Em (a), foi construído um modelo teórico matemático do
funcionamento de um equipamento perfusional, utilizando principalmente os
conceitos da mecânica dos fluidos. Com base nas equações obtidas, foi proposto
um método de compensação baseado em software das interferências geradas com
a mudança de decúbito do paciente. Em (b), o método proposto foi efetivamente
implementado em um software comercial para a realização de exames de
manometria esofágica de alta resolução. Em (c), o software desenvolvido foi
submetido a ensaios laboratoriais, e os resultados colhidos foram comparados aos
previstos teoricamente. Em (d), foram realizados exames em cinco voluntários para
verificar a usabilidade do software em condições reais. Resultados: Não foram
encontradas diferenças significativas (p=0,3) entre os valores teóricos previstos em
(a) e implementados em (b) e os obtidos experimentalmente em (c). Nos testes in vivo (d), a análise dos exames em ambas as posições pôde ser realizada
normalmente, as interferências foram eliminadas e os gráficos apresentaram boa
continuidade. Conclusão: O método proposto de compensação matemática
baseada em software na mudança de posição do paciente em exames de
manometria esofágica perfusional é factível e acurado.
Objective: To validate a software-based mathematical compensation method for the interference caused by changing the patient's position in perfusional esophageal manometry exams. Methods: The work was carried out in four stages: a) physical and mathematical modeling, b) software implementation, c) ex-vivo tests and d) in vivo tests. In (a), a theoretical mathematical model of the operation of a perfusion equipment was constructed, using mainly the concepts of fluid mechanics. Based on the equations obtained, a software-based compensation method for the interference generated when there is a change in the patient's position was proposed. In (b), the proposed method was effectively implemented in a commercial software to perform high resolution esophageal manometry exams. In (c), the developed software underwent laboratory tests, and the measurements were compared to those predicted theoretically. In (d), exams were carried out on five volunteers to verify the usability of the software in real conditions. Results: No significant differences were found (p=0.3) between the theoretical values predicted in (a) and implemented in (b) and those obtained experimentally in (c). In the in-vivo tests, the analysis of exams in both positions could be carried out seamlessly by the operator, the interferences were eliminated and the graphs presented good continuity. Conclusion: The proposed software-based mathematical compensation method for changing the patient's position in perfusion esophageal manometry examinations is feasible and accurate.
Objective: To validate a software-based mathematical compensation method for the interference caused by changing the patient's position in perfusional esophageal manometry exams. Methods: The work was carried out in four stages: a) physical and mathematical modeling, b) software implementation, c) ex-vivo tests and d) in vivo tests. In (a), a theoretical mathematical model of the operation of a perfusion equipment was constructed, using mainly the concepts of fluid mechanics. Based on the equations obtained, a software-based compensation method for the interference generated when there is a change in the patient's position was proposed. In (b), the proposed method was effectively implemented in a commercial software to perform high resolution esophageal manometry exams. In (c), the developed software underwent laboratory tests, and the measurements were compared to those predicted theoretically. In (d), exams were carried out on five volunteers to verify the usability of the software in real conditions. Results: No significant differences were found (p=0.3) between the theoretical values predicted in (a) and implemented in (b) and those obtained experimentally in (c). In the in-vivo tests, the analysis of exams in both positions could be carried out seamlessly by the operator, the interferences were eliminated and the graphs presented good continuity. Conclusion: The proposed software-based mathematical compensation method for changing the patient's position in perfusion esophageal manometry examinations is feasible and accurate.