Estudo dos parâmetros de pastas cerâmicas para a fabricação de scaffolds de fosfato de cálcio por robocasting
Data
2019-11-18
Autores
Cunha, Victor Ribeiro da 
Orientadores
Motisuke, Mariana
Tipo
Trabalho de conclusão de curso
Título da Revista
ISSN da Revista
Título de Volume
Resumo
O robocasting é uma técnica não-convencional de manufatura aditiva que possibilita a fabricação de peças com geometria complexa por meio da extrusão de uma pasta cerâmica depositando camada a camada utilizando modelagem 3D. Essa tecnologia garante precisão no controle da arquitetura interna dos poros e sua utilização está sendo explorada intensamente na engenharia tecidual, permitindo a fabricação de substitutos biológicos a base de fosfatos de cálcio para promover a regeneração óssea. Os scaffolds, ou estruturas-suporte, são matrizes de biomaterial que permitem o cultivo celular com a finalidade de reparar ou regenerar tecidos ósseos por meio de sua biocompatibilidade, bioreabsorção e ausência de toxicidade ao meio biológico. Utilizar a técnica de robocasting na fabricação de scaffolds é vantajoso pois essa técnica permite a manufatura da peça com maior precisão, possibilitando geometrias mais complexas e arquitetura de poros bem definida, obtendo-se então garantia e eficiência na aplicação clínica desse suporte. Neste trabalho foi realizado um levantamento bibliográfico sobre os parâmetros da pasta de fosfato de cálcio a ser utilizada na técnica de robocasting com o objetivo de produzir scaffolds, assim fazendo com que o processamento seja otimizado para que o produto final apresente bons resultados em aplicações futuras.
Robocasting is a non-conventional additive manufacturing technique that enables the manufacturing of parts with complex geometry by extruding a ceramic paste that is deposited layer by layer from a 3D modeling. This technology guarantees precision in the control of the internal architecture of the pores so its use is being explored intensely in tissue engineering, allowing the manufacture of biological substitutes based on calcium phosphates to promote bone regeneration. The scaffolds, or support structures, are biomaterial matrices that allow cell culture with the purpose of repairing or regenerating bone tissues due to their biocompatibility, bioreabsorption and absence of toxicity to the biological medium. Using the technique of robocasting in scaffolds manufacture is advantageous since this technique allows the development of a piece with greater precision, thus allowing more complex geometries and architecture of well-defined pores, obtaining then a guarantee of its efficiency in the clinical application of this support. In this work a bibliographic survey was made on the parameters of calcium phosphate paste to be used in robocasting technique with the objective of producing scaffolds, thus making the processing optimized to ensure good results for the end product in future applications
Robocasting is a non-conventional additive manufacturing technique that enables the manufacturing of parts with complex geometry by extruding a ceramic paste that is deposited layer by layer from a 3D modeling. This technology guarantees precision in the control of the internal architecture of the pores so its use is being explored intensely in tissue engineering, allowing the manufacture of biological substitutes based on calcium phosphates to promote bone regeneration. The scaffolds, or support structures, are biomaterial matrices that allow cell culture with the purpose of repairing or regenerating bone tissues due to their biocompatibility, bioreabsorption and absence of toxicity to the biological medium. Using the technique of robocasting in scaffolds manufacture is advantageous since this technique allows the development of a piece with greater precision, thus allowing more complex geometries and architecture of well-defined pores, obtaining then a guarantee of its efficiency in the clinical application of this support. In this work a bibliographic survey was made on the parameters of calcium phosphate paste to be used in robocasting technique with the objective of producing scaffolds, thus making the processing optimized to ensure good results for the end product in future applications