Tramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trial

Tramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trial

Author Giraldes, Ana Laura Albertoni Autor UNIFESP Google Scholar
Sousa, Angela Maria Google Scholar
Slullitel, Alexandre Google Scholar
Guimaraes, Gabriel Magalhaes Nunes Google Scholar
Santos, Melina Genevieve Mary Egan Google Scholar
Pinto, Renata Evangelista Google Scholar
Ashmawi, Hazem Adel Google Scholar
Sakata, Rioko Kimiko Autor UNIFESP Google Scholar
Abstract Study Objective: The purpose of this trial was to assess if tramadol wound infiltration is superior to intravenous (IV) tramadol after minor surgical procedures in children because tramadol seems to have local anesthetic like effect. Design: Randomized double-blind controlled trial. Setting: Postanesthesia care unit. Patients: Forty children, American Society of Anesthesiologists physical status I or II, scheduled to elective inguinal hernia repair. Interventions: Children were randomly distributed in 1 of 2 groups: IV tramadol (group 1) or subcutaneous infiltration with tramadol (group 2). At the end of the surgery, group 1 received 2 mg/kg tramadol (3 mL) by IV route and 3-mL saline into the surgical wound; group 2 received 2 mg/kg tramadol (3 mL) into the surgical wound and 3-mL saline by IV route. Measurements: In the postanesthesia care unit, patients were evaluated for pain intensity, nausea and vomiting, time to first rescue medication, and total rescue morphine and dipyrone consumption. Main Results: Pain scores measured during the postanesthesia recovery time were similar between groups. Time to first rescue medication was shorter, but not statistically significant in the IV group. The total dose of rescue morphine and dipyrone was also similar between groups. Conclusions: We concluded that tramadol was effective in reducing postoperative pain in children, and there was no difference in pain intensity, nausea and vomiting, or somnolence regarding IV route or wound infiltration. (C) 2016 Elsevier Inc. All rights reserved.
Keywords Infiltration anesthesia
Intravenous administration
Postoperative pain
xmlui.dri2xhtml.METS-1.0.item-coverage New York
Language English
Date 2016
Published in Journal Of Clinical Anesthesia. New York, v. 28, p. 62-66, 2016.
ISSN 0952-8180 (Sherpa/Romeo, impact factor)
Publisher Elsevier Science Inc
Extent 62-66
Access rights Closed access
Type Article
Web of Science ID WOS:000369194300013

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