Postnatal outcomes of infants with gastroschisis: a 5-year follow-up in a tertiary referral center in Brazil

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2016
Autores
Carvalho, Natalia Silva [UNIFESP]
Helfer, Talita Micheletti [UNIFESP]
Serni, Priscila de Oliveira [UNIFESP]
Terasaka, Ohanna Ana [UNIFESP]
Boute, Tatiane [UNIFESP]
Araujo Junior, Edward [UNIFESP]
Nardozza, Luciano Marcondes Machado [UNIFESP]
Moron, Antonio Fernandes [UNIFESP]
Rolo, Liliam Cristine [UNIFESP]
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Objective: The aim of this study was to evaluate postnatal outcomes in fetuses with gastroschisis.Methods: This is a retrospective study (2009-2013) of patients with gastroschisis at the Hospital SAo Paulo (Federal University of SAo Paulo, Brazil).Results: A total of 44 infants with gastroschisis were examined. The mean maternal age was 21.1 years and mean gestational age at delivery was 36.1 weeks. Delivery occurred before 34 weeks in 13.6%, between 34 and 36 weeks and 6d in 40.9%, and after 37 weeks in 45.5%. The mean birth weight was 2349g, with 37.2% small-for-gestational age infants. The mean umbilical cord blood pH was 7.32. Bowel resection and delayed fascial closure was performed in 14.6% and 19.5%, respectively. The mean hospitalization time in the neonatal intensive care unit was 52.7d. Neonatal infection was detected in 52.4%, with a positive blood culture; 77.3% of those cases were coagulase negative staphylococci. The overall rate of mortality was 25%; 18.2% before birth, 45.4% during the neonatal period, and 36.4% in infants. The main cause of postnatal death was septicemia (55.5%).Conclusions: Despite advances in perinatal care and surgical techniques, infants with gastroschisis still present high rates of complications and death.
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Journal Of Maternal-Fetal & Neonatal Medicine. Abingdon, v. 29, n. 3, p. 418-422, 2016.
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