Nanobiotechnology of Carbon Dots: A Review

Nanobiotechnology of Carbon Dots: A Review

Author Duran, Nelson Google Scholar
Simoes, Mateus B. Google Scholar
de Moraes, Ana C. M. Google Scholar
Favaro, Wagner J. Google Scholar
Seabra, Amedea B. Autor UNIFESP Google Scholar
Abstract In recent years, carbon dots (CDs) have gained increasing attention owing to their unique properties and enormous potential for several biomedical and technological applications. CDs are biocompatible, have a small size with a relatively large surface area, are photostable, and have customizable photoluminescence properties. This review is divided into the following discussions of CDs: general definitions

an overview of recent reviews

methods of green and classical synthesis

applications in bioimaging, involving supercapacitors, nanocarriers and nanomedicine

toxicological evaluations (including cytotoxic, genotoxic and anti-cancer properties of CDs)

their conjugation with enzymes, biosensors, and cell labeling. Finally the remaining drawbacks and challenges of CD applications are highlighted. In this context, this article aims to provide critical insight and inspire further developments in the synthesis and application of CDs.
Keywords Bioimaging
Carbon Dots
CD Synthesis
Cell Labeling
Drug Delivery
Gene Delivery
xmlui.dri2xhtml.METS-1.0.item-coverage Valencia
Language English
Sponsor FAPESP
NanoBioss (MCTI)
Brazilian Network on Nanotoxicology (MCTI/CNPq)
Grant number FAPESP: 2012/17053-7
FAPESP: 2012/22612-5
Date 2016
Published in Journal Of Biomedical Nanotechnology. Valencia, v. 12, n. 7, p. 1323-1347, 2016.
ISSN 1550-7033 (Sherpa/Romeo, impact factor)
Publisher Amer Scientific Publishers
Extent 1323-1347
Access rights Closed access
Type Article
Web of Science ID WOS:000378788600001

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