Neuropsychiatric Lupus in clinical practice
Data
2016
Autores
Alessi, Helena 
Dutra, Livia Almeida
Pedroso, Jose Luiz
Toso, Fabio Fieni
Mostrar mais
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs, characterized by the production of autoantibodies and the development of tissue injury. The etiology of SLE is partially known, involving multiple genetic and environmental factors. As many as 50% of patients with SLE have neurological involvement during the course of their disease. Neurological manifestations are associated with impaired quality of life, and high morbidity and mortality rates. Nineteen neuropsychiatric syndromes have been identified associated with SLE, and can be divided into central and peripheral manifestations. This article reviews major neuropsychiatric manifestations in patients with SLE and discusses their clinical features, radiological findings and treatment options.
Descrição
Citação
Arquivos De Neuro-Psiquiatria. Sao Paulo Sp, v. 74, n. 12, p. 1021-1030, 2016.