A new equationto predict peak VO2 in obese patients during cardiopulmonary exercise testing
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2018
Autores
Barbosa, Alan Carlos Brisola [UNIFESP]
Sperandio, Evandro Fornias [UNIFESP]
Gonze, Bárbara de Barros [UNIFESP]
Spina, Giovanna Domingues [UNIFESP]
Arantes, Rodolfo Leite
Gagliardi, Antonio Ricardo de Toledo
Romiti, Marcello
Dourado, Victor Zuniga [UNIFESP]
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We aimed to develop an equationto predict peak VO2 in obese subjects undergoing CPET. In addition, we evaluated and compared three published equations. We randomized 346 obese subjects undergoing CPET into a group for developing the equation(n=272) and a group for cross-validation (n=74), compared through the Bland and Altman method. Height, sex and age were responsible for 85<bold></bold>5% of total variability of the peak VO2. Additional 1% and 0<bold></bold>7% of the variability were, respectively, explained by physical inactivity and diabetes. The equation devised was as follows: The mean difference between the estimated and measured peak VO2 was 7mlmin(-1), with a 23<bold></bold>9% bias. Published equations overestimated the peak VO2 by 35<bold></bold>3%, 49<bold></bold>1% and 46<bold></bold>2% bias. The equationdeveloped in this study performed better in predicting peak VO2 in obese adults improving ramp protocol design and CRF evaluations in obese subjects.
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Clinical Physiology And Functional Imaging. Hoboken, v. 38, n. 3, p. 462-467, 2018.