Author |
Moreira, Barbara V.
![]() ![]() Muraca, Ana Carolina A. ![]() ![]() Raminelli, Cristiano ![]() ![]() |
Abstract | A modular approach for the synthesis of functionalized silylbiaryl triflates has been developed. Iodinated silylaryl triflates were prepared via a gram-scale diiodination reaction, followed by a one-flask transformation, in 42-52% overall yield. The iodinated silylaryl triflates were subjected to a novel chemoselective Suzuki reaction with arylboronic acids, using PdCl2(PPh3)(2) as catalyst and K2CO3 as base in THF/H2O (1:1) at 80 degrees C for 24 hours, which afforded silylbiaryl triflates in 47-81% yield. |
Keywords |
iodinated silylaryl triflates
chemoselective cross-coupling Suzuki reaction silylbiaryl triflates benzyne chemistry |
xmlui.dri2xhtml.METS-1.0.item-coverage | Stuttgart |
Language | English |
Sponsor |
Sao Paulo Research Foundation (FAPESP)
FAPESP |
Grant number |
|
Date | 2017 |
Published in | Synthesis-Stuttgart. Stuttgart, v. 49, n. 5, p. 1093-1102, 2017. |
ISSN | 0039-7881 (Sherpa/Romeo, impact factor) |
Publisher | Georg Thieme Verlag Kg |
Extent | 1093-1102 |
Origin |
|
Access rights | Closed access |
Type | Article |
Web of Science ID | WOS:000398093000020 |
URI | https://repositorio.unifesp.br/handle/11600/55033 |
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