What do Cochrane systematic reviews say about non-pharmacological interventions for treating cognitive decline and dementia?

What do Cochrane systematic reviews say about non-pharmacological interventions for treating cognitive decline and dementia?

Author Vilela, Vitoria Carvalho Autor UNIFESP Google Scholar
Pacheco, Rafael Leite Autor UNIFESP Google Scholar
Cruz Latorraca, Carolina Oliveira Autor UNIFESP Google Scholar
Pachito, Daniela Vianna Autor UNIFESP Google Scholar
Riera, Rachel Autor UNIFESP Google Scholar
Abstract BACKGROUND: Dementia is a highly prevalent condition worldwide. Its chronic and progressive presentation has an impact on physical and psychosocial characteristics and on public healthcare. Our aim was to summarize evidence from Cochrane reviews on non-pharmacological treatments for cognitive disorders and dementia. DESIGN AND SETTING: Review of systematic reviews, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo. METHODS: Cochrane reviews on non-pharmacological interventions for cognitive dysfunctions and/or type of dementia were included. For this, independent assessments were made by two authors. RESULTS: Twenty-four reviews were included. These showed that carbohydrate intake and validation therapy may be beneficial for cognitive disorders. For dementia, there is a potential benefit from physical activity programs, cognitive training, psychological treatments, aromatherapy, light therapy, cognitive rehabilitation, cognitive stimulation, hyperbaric oxygen therapy in association with donepezil, functional analysis, reminiscence therapy, transcutaneous electrical stimulation, structured decision-making on feeding options, case management approaches, interventions by non-specialist healthcare workers and specialized care units. No benefits were found in relation to enteral tube feeding, acupuncture, Snoezelen stimulation, respite care, palliative care team and interventions to prevent wandering behavior. CONCLUSION: Many non-pharmacological interventions for patients with cognitive impairment and dementia have been studied and potential benefits have been shown. However, the strength of evidence derived from these studies was considered low overall, due to the methodological limitations of the primary studies.
Keywords Dementia
Alzheimer disease
Evidence-based practice
Evidence-based medicine
xmlui.dri2xhtml.METS-1.0.item-coverage Sao Paulo
Language English
Date 2017
Published in Sao Paulo Medical Journal. Sao Paulo, v. 135, n. 3, p. 309-320, 2017.
ISSN 1516-3180 (Sherpa/Romeo, impact factor)
Publisher Associacao Paulista Medicina
Extent 309-320
Origin http://dx.doi.org/10.1590/1516-3180.2017.0092060617
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000406339500015
SciELO ID S1516-31802017000300309 (statistics in SciELO)
URI https://repositorio.unifesp.br/handle/11600/54517

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