Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis

Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis

Author Abboud, Cely Saad Google Scholar
Rao, Gauri G. Google Scholar
Souza, Ercilia E. Google Scholar
Zavascki, Alexandre P. Google Scholar
Kiffer, Carlos Autor UNIFESP Google Scholar
Abstract A retrospective cohort study, were evaluated: polymyxin B plus aminoglycosides or polymyxin B plus other antibiotics. Any degree of acute kidney injury occurred in 26 (86.6%) patients. The median time to acute kidney injury was 6.0 (95% CI 3-14) days in the polymyxin-aminoglycoside containing regimen group, against 27.0 (95% CI 6-42) days in the polymyxin with other antimicrobial combinations group (p = 0.03). Polymyxin B with aminoglycosides group progressed faster to any degree of renal dysfunction. (C) 2017 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. This is an open access article under the CC BY-NC-ND license.
Keywords AKI
CRE
Polymyxins
Aminoglicosides
xmlui.dri2xhtml.METS-1.0.item-coverage Rio De Janeiro
Language English
Sponsor Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP
Grant number FAPESP: 2108-3/2014
Date 2018
Published in Brazilian Journal Of Infectious Diseases. Rio De Janeiro, v. 22, n. 1, p. 51-54, 2018.
ISSN 1413-8670 (Sherpa/Romeo, impact factor)
Publisher Elsevier Brazil
Extent 51-54
Origin http://dx.doi.org/10.1016/j.bjid.2017.10.006
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000432647100009
SciELO ID S1413-86702018000100051 (statistics in SciELO)
URI https://repositorio.unifesp.br/handle/11600/54301

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