Dissemination of Multidrug-Resistant Proteus mirabilis Clones Carrying a Novel Integron- Borne bla(IMP)-(1) in a Tertiary Hospital

Dissemination of Multidrug-Resistant Proteus mirabilis Clones Carrying a Novel Integron- Borne bla(IMP)-(1) in a Tertiary Hospital

Author Ramos, Ana Carolina Autor UNIFESP Google Scholar
Cayo, Rodrigo Autor UNIFESP Google Scholar
Carvalhaes, Cecilia Godoy Autor UNIFESP Google Scholar
Jove, Thomas Google Scholar
da Silva, Greice Pereira Google Scholar
Paschoin Sancho, Fernanda Maciel Google Scholar
Chagas-Neto, Thomas Autor UNIFESP Google Scholar
Servolo Medeiros, Eduardo Alexandrino Autor UNIFESP Google Scholar
Gales, Ana Cristina Autor UNIFESP Google Scholar
Abstract This study aimed to characterize multidrug-resistant Proteus mirabilis clones carrying a novel class 1 integron-borne bla(IMP)-1. In1359 was inserted into a large conjugative plasmid that also carried bla(CTX-M-2). The production of carbapenemases in Enterobacteriaceae that are intrinsically resistant to polymyxins and tigecycline is very worrisome, representing a serious challenge to clinicians and infection control teams.
Keywords IMP-1
In1359
KPC-2
Proteus mirabilis
RmtB-1
aacA4-26
class 1 integron
clones
multidrug resistance
xmlui.dri2xhtml.METS-1.0.item-coverage Washington
Language English
Sponsor Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
National Council for Science and Technological Development (CNPq)
Bayer
Merck Sharp Dohme
Pfizer
Grant number CAPES: PNPD 20131991
CNPq: 305535/2014-5
Date 2018
Published in Antimicrobial Agents And Chemotherapy. Washington, v. 62, n. 2, p. -, 2018.
ISSN 0066-4804 (Sherpa/Romeo, impact factor)
Publisher Amer Soc Microbiology
Extent -
Origin http://dx.doi.org/10.1128/AAC.01321-17
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000423443600007
URI https://repositorio.unifesp.br/handle/11600/54215

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