Imaging findings in congenital Zika virus infection syndrome: an update
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2018
Autores
de Souza, Andrea Silveira
de Oliveira-Szjenfeld, Patricia Soares [UNIFESP]
de Oliveira Melo, Adriana Suely
Moreira de Souza, Luis Alberto
Medeiros Batista, Alba Gean
Tovar-Moll, Fernanda
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Background Zika virus (ZIKV) is a neurotropic and neurotoxic RNA Flavivirus prompt to cause severe fetal brain dysmorphisms during pregnancy, a period of rapid and critical central nervous system development. Awide range of clinicoradiological findings of congenital ZIKV infections were reported in the literature, such as microcephaly, overlapping sutures, cortical migrational and corpus callosum abnormalities, intracranial calcifications, ventriculomegaly, brain stem and cerebellar malformations, spinal cord involvement, and joint contractures. ZIKV is also related to other severe neurological manifestations in grown-up individuals such as Guillain-Barre syndrome and encephalomyelitis. Our purpose is to review the radiological central nervous system abnormalities of congenital ZIKV infection syndrome on different imaging modalities.
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Childs Nervous System. New York, v. 34, n. 1, p. 85-93, 2018.