Vancomycin-associated linear IgA disease mimicking toxic epidermal necrolysis
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2016
Authors
Pereira, Amanda Regio [UNIFESP]
Siqueira Pinheiro, Jhonatan Rafael [UNIFESP]
Enokihara, Mílvia Maria Simões e Silva [UNIFESP]
Moura, Luis Henrique Barbizan de [UNIFESP]
Pasin, Victor Pavan [UNIFESP]
Porro, Adriana Maria [UNIFESP]
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Abstract
Linear IgA dermatosis is a rare subepidermal autoimmune blistering disease characterized by linear deposition of IgA along the basement membrane zone. In the last three decades, many different drugs have been associated with the druginduced form of the disease, especially vancomycin. We report a case of vancomycin-induced linear IgA disease mimicking toxic epidermal necrolysis. The aim of this work is to emphasize the need to include this differential diagnosis in cases of epidermal detachment and to review the literature on the subject and this specific clinical presentation.
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Anais Brasileiros De Dermatologia. Rio De Janeiro Rj, v. 91, n. 5, p. 35-38, 2016.