Metastasis from Oral Cancer: An Overview

Metastasis from Oral Cancer: An Overview

Author Noguti, Juliana Autor UNIFESP Google Scholar
Moura, Carolina Foot Gomes de Autor UNIFESP Google Scholar
Jesus, Gustavo Protasio Pacheco de Autor UNIFESP Google Scholar
Silva, Victor Hugo Pereira da Autor UNIFESP Google Scholar
Hossaka, Thais Ayako Autor UNIFESP Google Scholar
Oshima, Celina Tizuko Fujiyama Autor UNIFESP Google Scholar
Ribeiro, Daniel Araki Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Oral cancer is a common neoplasm worldwide. Its incidence and mortality have also increased over the past decades. It is characterized by poor prognosis and a low survival rate despite sophisticated surgical and radiotherapeutic modalities. Metastasis of oral cancer is a complex process involving detachment of cells from tumor tissue, regulation of cell motility and invasion, proliferation and evasion through the lymphatic system or blood vessels. In this review, we will focus on the current knowledge in metastasis from oral cancer regarding facts, such as incidence; stage, histopathology and grade of primary tumor; clinical manifestations; diagnosis; and treatment. Certainly, such information will contribute to the understanding of oral cancer pathogenesis.
Keywords Oral cancer
Language English
Date 2012-09-01
Published in Cancer Genomics & Proteomics. Athens: Int Inst Anticancer Research, v. 9, n. 5, p. 329-335, 2012.
ISSN 1109-6535 (Sherpa/Romeo, impact factor)
Publisher Int Inst Anticancer Research
Extent 329-335
Access rights Open access Open Access
Type Review
Web of Science ID WOS:000309243400008

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