Validation of the Brazilian version of Chronic Liver Disease Questionnaire
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Date
2013-02-01
Authors
Mucci, Samantha [UNIFESP]
Citero, Vanessa de Albuquerque [UNIFESP]
Gonzalez, Adriano Miziara [UNIFESP]
Geocze, Luciana [UNIFESP]
Geocze, Stephan [UNIFESP]
Lopes Filho, Gaspar de Jesus [UNIFESP]
De Marco, Mario Alfredo [UNIFESP]
Parise, Edison Roberto [UNIFESP]
Nogueira Martins, Luiz Antonio [UNIFESP]
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Abstract
Purpose the aim of this study was to validate the Chronic Liver Disease Questionnaire (CLDQ) for use in Brazilian population.Method A total of 200 patients with chronic liver disease and varying disease severity answered a socio-demographic questionnaire, t CLDQ, and the Medical Outcome Study Short Form 36 (SF-36). Patients returned in 1-15 days to answer CLDQ again. the Cronbach's alpha of the total CLDQ score was 0.95 and fluctuated between 0.69 and 0.83 in its six domains.Results the intra-class correlation between total CLDQ scores in two evaluations was 0.97 and in all domains was >0.93. CLDQ was moderately correlated with the SF-36, 0.63 (total CLDQ vs. vitality, SF-36), 0.62 (CLDQ and mental health, SF-36), 0.62 (preoccupation, CLDQ, vs. General Health, SF-36), 0.59 (fatigue, CLDQ, vs. vitality, SF-36), 0.59 (activity, CLDQ, vs. vitality, SF-36), and 0.59 (fatigue, CLDQ, vs. mental health, SF-36). the highest scores were found in non-cirrhotic group. Child A patients had higher average scores than Child B and C groups in all domains, while patients with MELD <15 scored higher than patients with MELD >= 15.Conclusion CLDQ-BR was validated in Brazilian population and was appropriate for use in patients with liver disease of different etiologies and degrees of severity.
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Quality of Life Research. Dordrecht: Springer, v. 22, n. 1, p. 167-172, 2013.