Validation of the Brazilian version of Chronic Liver Disease Questionnaire

Validation of the Brazilian version of Chronic Liver Disease Questionnaire

Author Mucci, Samantha Autor UNIFESP Google Scholar
Citero, Vanessa de Albuquerque Autor UNIFESP Google Scholar
Gonzalez, Adriano Miziara Autor UNIFESP Google Scholar
Geocze, Luciana Autor UNIFESP Google Scholar
Geocze, Stephan Autor UNIFESP Google Scholar
Lopes Filho, Gaspar de Jesus Autor UNIFESP Google Scholar
De Marco, Mario Alfredo Autor UNIFESP Google Scholar
Parise, Edison Roberto Autor UNIFESP Google Scholar
Nogueira Martins, Luiz Antonio Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Purpose the aim of this study was to validate the Chronic Liver Disease Questionnaire (CLDQ) for use in Brazilian population.Method A total of 200 patients with chronic liver disease and varying disease severity answered a socio-demographic questionnaire, t CLDQ, and the Medical Outcome Study Short Form 36 (SF-36). Patients returned in 1-15 days to answer CLDQ again. the Cronbach's alpha of the total CLDQ score was 0.95 and fluctuated between 0.69 and 0.83 in its six domains.Results the intra-class correlation between total CLDQ scores in two evaluations was 0.97 and in all domains was >0.93. CLDQ was moderately correlated with the SF-36, 0.63 (total CLDQ vs. vitality, SF-36), 0.62 (CLDQ and mental health, SF-36), 0.62 (preoccupation, CLDQ, vs. General Health, SF-36), 0.59 (fatigue, CLDQ, vs. vitality, SF-36), 0.59 (activity, CLDQ, vs. vitality, SF-36), and 0.59 (fatigue, CLDQ, vs. mental health, SF-36). the highest scores were found in non-cirrhotic group. Child A patients had higher average scores than Child B and C groups in all domains, while patients with MELD <15 scored higher than patients with MELD >= 15.Conclusion CLDQ-BR was validated in Brazilian population and was appropriate for use in patients with liver disease of different etiologies and degrees of severity.
Keywords Quality of life
Chronic liver disease
Language English
Date 2013-02-01
Published in Quality of Life Research. Dordrecht: Springer, v. 22, n. 1, p. 167-172, 2013.
ISSN 0962-9343 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 167-172
Access rights Closed access
Type Article
Web of Science ID WOS:000315279300020

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