Physical therapy and psychological intervention normalize cortisol levels and improve vitality in women with endometriosis

Physical therapy and psychological intervention normalize cortisol levels and improve vitality in women with endometriosis

Author Petrelluzzi, Karina Friggi Sebe Autor UNIFESP Google Scholar
Garcia, Marcia Carvalho Autor UNIFESP Google Scholar
Petta, Carlos Alberto Google Scholar
Ribeiro, Daniel Araki Autor UNIFESP Google Scholar
Oliveira-Monteiro, Nancy Ramacciotti de Autor UNIFESP Google Scholar
Céspedes, Isabel Cristina Autor UNIFESP Google Scholar
Spadari, Regina Celia Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade Estadual de Campinas (UNICAMP)
Abstract There is as yet no effective treatment for endometriosis. the objective of this study was to evaluate the effectiveness of submitting women with endometriosis and chronic pelvic pain to a therapeutic protocol involving physical and psychological therapy. Twenty-six female volunteers were submitted to a treatment protocol consisting of 2.5-h sessions, once a week for 10 weeks. We applied a Visual Analogue Scale, the Perceived Stress Questionnaire (PSQ), and the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Morning, afternoon, and evening levels of cortisol were determined in saliva samples. the PSQ scores were significantly lower after treatment, whereas the scores for the SF-36 vitality and physical functioning domains were significantly higher. Salivary cortisol levels were higher after treatment in the samples collected in the morning, but not in those collected in the afternoon or evening. the post-treatment cortisol levels were similar to those reported for healthy women. There were positive correlations between vitality, role emotional, social functioning, and mental health, and negative correlations to perceived stress. in conclusion, the physical and psychological intervention protocol applied in this study to women suffering of endometriosis was effective in reducing perceived stress, normalizing cortisol levels, increasing vitality and improving physical functioning.
Keywords Awakening cortisol response
Chronic pelvic pain
Perceived stress levels
Therapeutic intervention
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Grant number FAPESP: 03/09173-3
Date 2012-12-01
Published in Journal of Psychosomatic Obstetrics and Gynecology. London: Informa Healthcare, v. 33, n. 4, p. 191-198, 2012.
ISSN 0167-482X (Sherpa/Romeo, impact factor)
Publisher Informa Healthcare
Extent 191-198
Access rights Closed access
Type Article
Web of Science ID WOS:000311684300006

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