Characterization of an integron carrying bla(IMP-1) and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital

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2007-07-01
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Mendes, Rodrigo Elisandro [UNIFESP]
Castanheira, Mariana [UNIFESP]
Toleman, Mark A.
Sader, Helio Silva [UNIFESP]
Jones, Ronald N.
Walsh, Timothy R.
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Seven bla(IMP-1)-harboring Acinetobacter sp. isolates and one Pseudomonas putida clinical isolate were recovered from hospitalized patients. All isolates possessed a class 1 integron, named In86, carrying the same cassette array [bla(IMP1), aac(6')-31, and aadA1], which was plasmid located in five of the isolates. This report describes the ability of nonfermentative nosocomial pathogens to acquire and disseminate antimicrobial resistance determinants.
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Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 51, n. 7, p. 2611-2614, 2007.
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