Navegando por Palavras-chave "tireoidite crônica autoimune"
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- ItemAcesso aberto (Open Access)A iodúria de pacientes portadores de tireopatias autoimunes em Santo andré, SP, é comparável à dos indivíduos normais e estável nos últimos dez anos(Sociedade Brasileira de Endocrinologia e Metabologia, 2009-02-01) Marino, Maria Angela Zaccarelli; Martins, Lourdes Conceição; Esteves, Roberto Z. [UNIFESP]; Kasamatsu, Teresa S. [UNIFESP]; Maciel, Rui Monteiro de Barros [UNIFESP]; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: Evaluate whether the increase of iodine in the diet would be the triggering factor for auto-immune thyropathies in the city of Santo André, SP. METHODS: Urinary iodine was determined in samples isolated from 58 patients, divided in 4 Groups, and in 13 normal individuals (controls). RESULTS: Urinary Iodine: Group 1 - hyperthyroidism = 203.5±152.71 µg/ L(mean±sd); Group 2 - hypothyroidism = 258.31±148,2 µg/L; Group 3 - chronic auto-immune thyroiditis = 244.29±191.6 µg/L; group 4 (Amiodarone) = 1157.5±261.8 µg/L; Group 5 - Controls = 262.31±146.2 µg/L. On comparing the means of urinary iodine among the groups, the means for groups 1, 2, 3, and 5 did not present significant differences (p>0.05), and all differed from group 4 (p<0.05). Urinary iodine obtained in groups 1, 2, 3 and 5, obtained in 2002-03, is not different from the values determined in students in 1994 in Santo André. CONCLUSION: This study shows evidence that iodine should not be considered as the responsible agent for auto-immune thyropathies in Santo André, and other environmental factors should be investigated.