Navegando por Palavras-chave "oldest old"

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    25(oh)vitamina d como preditor de desfechos e óbito em idosos longevos
    (Universidade Federal de São Paulo (UNIFESP), 2016-10-26) Pontes, Tatiana Elias de [UNIFESP]; Cendoroglo, Maysa Seabra Cendoroglo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    25(OH) Vitamin D as Predictor of Outcomes and Death in Oldest Old One of the greatest cultural achievements of a people in their humanization process is the aging of its population, reflecting the improvement of living conditions. Some factors that contribute to active aging can benefit the raising number of oldest old people. Vitamin D and life style have shown impact on functionality and mortality. That context, this study has aimed to evaluate the relationship between serum levels of 25(OH) Vit D, outdoor activity, poor outcomes and death in independent oldest old. We selected 258 community-dwelling and independent elderly people with 80 years old or more, accompanied the Geriatrics and Gerontology Division, Federal University of São Paulo. We dose serum levels of 25(OH)D and apply a questionnaire on skin type, sun exposure and falls. We evaluated the mortality through the death certificate or register in medical records from April 2010 to March 2016. During the survival analysis, we have used the models of Kaplan-Meier and Cox. Around 70.5% were women between 80 to 89 years old (80.2%), 38.8% had daily sunlight exposure > 15 minutes and 20.1% were chronic fallers. Regarding 25(OH)D, 9.3% had serum levels < 10 ng/mL, while 76.4% between 10-30 ng/mL and 14.3% showed values > 30 ng/mL. During the observational period, 65.9% of the old oldest have stayed independent, and 17.1% have deceased. The analysis of survival time have shown that men (HR=2.7, p=0.003), over 90 years old (HR= 4.12, p < 0.001), with levels of 25(OH)VitD < 10 ng/mL (HR=3.2, p=0.004) and chronic fallers (HR=1.97, p=0.042) have shown a lower survival in comparison to the other oldest old; while women, aged 80-89 years, with a level of 25(OH) VitD > 10ng/mL and not chronic fallers, have characterized the lower risk group. Thus, we have identified that insufficient levels of 25(OH) VitD contribute to increased risk of death in the oldest old.
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    Ultrasonographic assessment of thyroid volume in oldest-old individuals
    (Sbem-Soc Brasil Endocrinologia & Metabologia, 2017) Duarte, Glaucia Cruzes [UNIFESP]; Quirino Araujo, Lara Miguel [UNIFESP]; Magalhaes Filho, Felix [UNIFESP]; Almada Filho, Clineu Mello [UNIFESP]; Cendoroglo, Maysa Seabra [UNIFESP]
    Objective: The aim of this study was to describe the relationship between thyroid volume and age, gender, anthropometric characteristics, and echogenicity in oldest-old subjects in an iodine-sufficient area. Subjects and methods: The study included 81 independent elderly individuals aged >= 80 years (65 [80.2%] women). We determined these individuals' anthropometric characteristics, body mass index (BMI), and lean body mass, as well as thyroid volume and echogenicity by ultrasonography. Results: We observed that octogenarians and nonagenarians had different profiles of thyroid echogenicity. The volume of the thyroid was smaller in nonagenarians than octogenarians (p = 0.012, r = 0.176), and subjects aged 80-89 years had more often hypoechoic glands than those aged >= 90 years (p = 0.01 versus 0.602). Conclusion: The identification of ultrasonographic differences in oldest-old individuals will contribute to establishing preclinical markers, such as echogenicity, to identify individuals at risk of developing autoimmune thyroid disease. Future prospective studies should identify if 80-89-year-old individuals with hypoechoic glands progress to hypothyroidism, and if the absence of changes in echogenicity (i.e. a normal thyroid parenchyma) would have a positive impact on longevity among nonagenarians.