Navegando por Palavras-chave "muscle weakness"
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- ItemSomente MetadadadosAcute action of aminophylline in patients with amyotrophic lateral sclerosis(Blackwell Publishing, 2007-05-01) Berto, M. C.; Filha, S. C.; Camelier, A.; Rosa, F. W.; Oliveira, A. de Souza Bulle; Jardim, J. R.; Universidade Federal de São Paulo (UNIFESP)Objective - This study investigated whether aminophylline has an acute effect on the muscle performance of patients with amyotrophic lateral sclerosis (ALS). the study was a randomized, double-blind, crossover against placebo. Materials and methods - Twenty-five patients (48.5 +/- 14.1 years) with ALS were evaluated by means of forced vital capacity (FVC), maximal mouth inspiratory and expiratory pressures (P-Imax/P-Emax) and endurance, maximum voluntary ventilation (MVV) and handgrip strength (HS); variables were measured before and after the patients received an intravenous infusion of aminophylline or placebo. Results - MVV (P < 0.02) and HS of the right and left hands (P = 0.05) increased after aminophylline infusion. There was a positive correlation between FVC and P-Imax (r = 0.80; P < 0.05); between MVV and P-Imax post-aminophylline, respectively (r = 0.77; P < 0.05). Serum aminophylline levels ranged from 5.3 to 10.5 mu g/mL (mean 7.30). Conclusion - the acute administration of aminophylline improves the endurance of respiratory muscles and increases handgrip strength in patients with ALS.
- ItemSomente MetadadadosProfile of isokinetic eccentric-to-concentric strength ratios of shoulder rotator muscles in elite female team handball players(Taylor & Francis Ltd, 2010-01-01) Andrade, Marilia Dos Santos [UNIFESP]; Fleury, Anna Maria [UNIFESP]; Barbosia de Lira, Claudio Andre; Dubas, Joao Paulo [UNIFESP]; Silva, Antonio Carlos da [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Federal de Goiás (UFG)The purpose of this study was to establish the isokinetic profile of shoulder rotator muscles strength in female handball players. Twenty-seven handball players performed concentric and eccentric strength tests of both dominant and non-dominant upper limbs on an isokinetic dynamometer. Internal and external rotator muscles peak torque was assessed at 1.05, 3.14, and 5.23 rad center dot s-1 in concentric mode and at 3.14 and 5.23 rad center dot s-1 in eccentric mode. Concentric balance ratio and functional ratio were obtained. Bi-lateral deficiency was compared. Concentric strength for internal and external rotation was significantly greater for the dominant than for the non-dominant limb for all speeds (P0.0001). for eccentric actions, internal rotator muscles were stronger in the dominant than the non-dominant limb (P0.0001) at both speeds. Concentric balance and functional balance ratios did not differ between sides at 3.14 rad center dot s-1 (P=0.1631), but at 5.23 rad center dot s-1 the functional balance ratio in the dominant limb was lower than for the non-dominant limb (P=0.0500). Although the dominant side was stronger than the non-dominant side, balance concentric ratios remained the same, with only the functional strength ratio different at 5.23 rad center dot s-1. Our results suggest that concentric strength exercises be used for internal and external rotators on the non-dominant side, and functional exercise that improves eccentric rotation strength for prevention programmes.