Navegando por Palavras-chave "meningeoma"
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- ItemAcesso aberto (Open Access)Meningeoma da goteira olfatória(Academia Brasileira de Neurologia - ABNEURO, 2006-03-01) Tella Jr, Osvaldo Inácio de [UNIFESP]; Paiva Neto, Manoel Antonio de [UNIFESP]; Herculano, Marco Antonio; Faedo Neto, Atílio; Universidade Federal de São Paulo (UNIFESP); Hospital Professor Edmundo Vasconcelos; Faculdade de Medicina de JundiaíOlfactory groove meningiomas compromise approximately 8-18% of intracranial meningiomas and harbor frequently large sizes when diagnosticated. We report 13 consecutive cases operated on Hospital São Paulo and Hospital Professor Edmundo Vasconcelos between 1995 and 2003. These patients were retrospectively studied regarding clinical preservation, surgical results and complications. The patients underwent uni or bifrontal craniotomies. There were nine complete resections including duramater and infiltrate bone and four patients with tumor removal and duramater coagulation. One patient died on post-operative period due to brain infarction and three patients had cerebrospinal fluid fistula that resolved. There were no symptomatic recurrence on the follow-up period of 3.3 years(range 11 m to 8 years). With current microsurgical techniques, these tumors can be resected safely with low morbidity.
- ItemAcesso aberto (Open Access)Meningeoma de goteira olfatória: relação entre achados clínico-radiológicos e índice proliferativo (Mib-1)(Academia Brasileira de Neurologia - ABNEURO, 2006-03-01) Paiva Neto, Manoel Antonio de [UNIFESP]; Tella Jr, Oswaldo Inácio de [UNIFESP]; Herculano, Marco Antonio [UNIFESP]; Stávale, João Norberto [UNIFESP]; Bonatteli, Antonio Pádua Furquim [UNIFESP]; Hospital Edmundo Vasconcelos; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: The aim of this study is to correlationate demografic, radiologic features and proliferative index defined by imunohistochemical expression of Mib-1 in olfactory groove meningiomas, and to observe possible predictive factors of recurrence of this tumor. METHOD: There were analysed demografic, clinical and radiological features of 15 patients with olfactory groove meningioma. Fifteen paraffin-embebed tumors were studied by imunohistochemical methods for the expression of proliferative index by the Mib-1. RESULTS: There was a statiscally positive correlation between tumoral and edema volumes. There was no correlation betweem Mib-1, tumoral volume, tumoral edema and frontal skull base abnormalities. Two cases with tumor recurrence had proliferative indices higher than the mean index. CONCLUSION: Larger tumors were more susceptible to develop peritumoral edema. The proliferative índex has no positive correlation with tumoral volume, edema volumes and skull base invasion, but probably it is associated with tumoral recurrence.