Navegando por Palavras-chave "hipertireoidismo"
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- ItemAcesso aberto (Open Access)Adenomas produtores de TSH: Relato de caso(Academia Brasileira de Neurologia - ABNEURO, 2002-03-01) Tella Jr, Oswaldo Inácio [UNIFESP]; Herculano, Marco Antonio; Delcelo, Rosana [UNIFESP]; Prandini, Mirto Nelso [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Faculdade de Medicina de Jundiaí Disciplina de NeurocirurgiaWe describe a rare case of thyroid-stimulating hormone-secreting pituitary adenoma in a patient with a clinical picture of hyperthyroidism, that developed bitemporal hemianopsia after four years of a known thyroid dysfunction. CT scan showed a pituitary tumor considered grade 2 and stage C according to Hardy-Vezina and Wilson. Treatment was surgical, initially by a transsphenoidal approach, in which only a biopsy was possible. The patient was then submitted to an orbital-pterional craniotomy with sub-total resection of the tumor. Complementary treatment was indicated with radiotherapy.
- ItemAcesso aberto (Open Access)A iodúria de pacientes portadores de tireopatias autoimunes em Santo andré, SP, é comparável à dos indivíduos normais e estável nos últimos dez anos(Sociedade Brasileira de Endocrinologia e Metabologia, 2009-02-01) Marino, Maria Angela Zaccarelli; Martins, Lourdes Conceição; Esteves, Roberto Z. [UNIFESP]; Kasamatsu, Teresa S. [UNIFESP]; Maciel, Rui Monteiro de Barros [UNIFESP]; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: Evaluate whether the increase of iodine in the diet would be the triggering factor for auto-immune thyropathies in the city of Santo André, SP. METHODS: Urinary iodine was determined in samples isolated from 58 patients, divided in 4 Groups, and in 13 normal individuals (controls). RESULTS: Urinary Iodine: Group 1 - hyperthyroidism = 203.5±152.71 µg/ L(mean±sd); Group 2 - hypothyroidism = 258.31±148,2 µg/L; Group 3 - chronic auto-immune thyroiditis = 244.29±191.6 µg/L; group 4 (Amiodarone) = 1157.5±261.8 µg/L; Group 5 - Controls = 262.31±146.2 µg/L. On comparing the means of urinary iodine among the groups, the means for groups 1, 2, 3, and 5 did not present significant differences (p>0.05), and all differed from group 4 (p<0.05). Urinary iodine obtained in groups 1, 2, 3 and 5, obtained in 2002-03, is not different from the values determined in students in 1994 in Santo André. CONCLUSION: This study shows evidence that iodine should not be considered as the responsible agent for auto-immune thyropathies in Santo André, and other environmental factors should be investigated.
- ItemAcesso aberto (Open Access)Vasculite cutânea induzida por propiltiouracil(Sociedade Brasileira de Reumatologia, 2008-02-01) Milanez, Fernanda Manente; Costa, Leonardo Atem Gonçalves A.; José, Fábio Freire [UNIFESP]; Enokihara, Milvia M. S. S. [UNIFESP]; Souza, Alexandre Wagner Silva de [UNIFESP]; Hospital do Servidor Público Estadual Francisco Morato de Oliveira; Universidade Federal de São Paulo (UNIFESP)The use of propylthiouracil (PTU) is associated with the development of different auto-antibodies, amongst them are antineutrophil cytoplasmic antibodies (ANCA) that are involved in the pathogenesis of ANCA associated systemic vasculitis. The case of a 46-years old woman who presented cutaneous vasculitis when taking PTU for Graves' disease is reported. Perinuclear ANCA (p-ANCA) was positive with titer > 1/320, but anti-myeloperoxidase antibodies were not detected. Skin biopsy showed leucocytoclastic vasculitis. The patient improved within ten days after withdrawing PTU and the resolution of hyperthyroidism was achieved with radioiodine (131I). The p-ANCA test remained positive > 1/320 eight months and four years after PTU withdrawal.