Navegando por Palavras-chave "genital prolapse"

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    Preservação uterina versus histerectomia no tratamento cirúrgico do prolapso genital: revisão sistemática e metanálise
    (Universidade Federal de São Paulo (UNIFESP), 2016-05-20) Oliveira, Sofia Andrade de [UNIFESP]; Castro, Rodrigo de Aquino Castro [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: genital prolapse is defined as the permanent displacement of any segment or vaginal pelvic organ from its usual location, covering the prolapse of the uterus or the vaginal walls. A hysterectomy has been the standard treatment for symptomatic uterine prolapse correction. With lifestyle change and with increasing concern with fertility and female sexual function, many patients ask the possibility of uterine preservation. Objective: conducting a meta-analysis with articles that prospectively have compared the uterine preservation and hysterectomy to correct uterine prolapse. Results: uterine preservation showed higher rate of recurrence and reoperation (CI:1.41-4.64, p = 0.002; CI:1:23 to 5:27, p=0.01). The mesh extrusion rate, operative time and blood loss were lower in uterine preservation techniques (CI:0.14-0.78, p=0.01; CI:-40.14,-12.73, p=0.0002; CI:-121.29,-12.22, p=0.02). There was a lower incidence of dyspareunia and higher febrile morbidity rate with uterine preservation, however, the difference was not statistically significant (CI:0.30-2:57, p=0.81, CI:0.32-4:46, p=0.80). The time of urinary catheterization, hospital stay, urinary retention rate and visceral injury rate had no difference between the groups (CI:-0.48-0:30, p = 0.65; CI:-0.17-0.04, p=0.23; IC:0.06-6.69, p=0.70, CI:0.03-2.83, p=0.29). Conclusion: histeropreservação in uterine prolapses determines higher rate of recurrence and reoperation, although require less surgical time with less blood loss and there is less screen extrusion rate when used.
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    Sulfated glycosaminoglycans of the vagina and perineal skin in pre- and postmenopausal women, according to genital prolapse stage
    (Springer, 2004-08-01) Bezerra, LRPS; Feldner, P. C.; Kati, L. M.; Girao, MJBC; Sartori, M. G.; Baracat, E. C.; Lima, G. R. de; Nader, H. B.; Dietrich, C. P.; Universidade Federal de São Paulo (UNIFESP)
    The aim of this study was to analyze the amount and types of sulfated glycosaminoglycans (GAGs) of the extracellular matrix (ECM) in the posterior vaginal wall and perineal skin in menacme and postmenopausal women, according to genital prolapse stage. Samples of vaginal tissue and perineal skin were obtained from 40 women who underwent vaginal surgery. Sulfated glycosaminoglycans were extracted by extensive tissue maxatase digestion, submitted to electrophoresis on agarose gel, and their concentrations were determined by densitometry. Dermatan sulphate (DS) was the predominant GAG, followed by chondroitin sulfate (CS) and heparan sulfate (HS). in the vagina there was a significant decrease in total GAGs, CS, DS and HS in postmenopausal women with prolapse stage 2 and 3 compared to the premenopausal group, independent of the stage. in stage 2 and 3 postmenopausal patients there was a significant decrease of DS and HS compared to the stage 1 postmenopausal group. in perineal skin there was no significant difference between total GAG amount, DS and HS. However, the amount of CS in premenopausal stage 1 patients was significantly than that in postmenopausal patients stage 1 and stages 2 and 3. in conclusions, there are quantitative and qualitative differences in GAGs of the ECM in vaginal wall and perineal skin between women in menacme and the postmenopause, according to genital prolapse stage.