Navegando por Palavras-chave "eletrorretinografia"

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    Causa clínicas de eletrorretinograma negativo em pacientes de hospital universitário
    (Universidade Federal de São Paulo (UNIFESP), 2015-12-31) Rocha, Daniel Martins [UNIFESP]; Berezovsky, Adriana [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: To determine the frequency and cause of electroretinography (ERG) negative scotopic over a period of 11 years and correlate the fundus findings, age, sex, visual acuity and family inbreeding. Methods: This retrospective cross-sectional observational study included 1612 patients, who were divided into two groups according to age, with 245 of the group of children and adolescents under the age of eighteen years of age (group 1) and in 1367 the adult group over the age of eighteen years of age (group 2) examined between March 2004 and July 2015 in Visual Electrophysiology Laboratory of the Department of Ophthalmology and Visual Sciences at the Federal University of São Paulo / Hospital Sao Paulo. Patients were selected who had negative ERG, or a significant reduction of amplitude of the b-wave so that the wave amplitude was lower than it, i.e., b / a ratio ? 1 at maximum scotopic ERG response. The level of statistical significance was taken as p ? 0.05. Results: Of the total sample, 41 (2.5%) patients had negative ERG, 27 adults (2.0%) and 14 children and adolescents (5.7%). Ages ranged from 0.5 to 78.1 years (mean 32.8 ± 20.5; median 28.6), and for group 1 0.5 to 17.0 years (12.2 ± 4.6 ; median 13.8) and for Group 2, 18.6 to 78.1 years (43.5 ± 17.0, median 38.5). Of the total, 23 patients (56.1%) were male and 18 (44.9%) were female. ERG negative bilateral was found in 29 patients (12 in Group 1, 17 in Group 2) and unilateral in 12 patients (Group 1 2, 10 for group 2). A family history of consanguinity was found in nine patients (21.9%). The average visual acuity in the better eye sight was 0.54 ± 0.54 logMAR of (20/70) and 0.73 ± 0.39 logMAR (20/107) for group 1 and 0.45 ± 0, 58 logMAR (20/56) for group 2. The visual acuity for the worst eye vision was 0.88 ± 0.69 logMAR (20/150) and 0.83 ± 0.41 logMAR (20 / 135) for group 1 and 0.91 ± 0.74 logMAR (20/186) for group 2. The changes most commonly found in the fundus were: atrophy of the retinal pigment epithelium in 34 patients (12 in group 1; 22 Group 2), pale papilla in 22 patients (14 in group 1, group 2, 8) and vascular attenuation of 22 patients (8 in group 1: 14 group 2). The most frequent diagnostic hypotheses were: retinitis pigmentosa (33.3%), juvenile retinoschisis (12.8%) and uveitis (12.8%). Conclusions: The negative ERG frequency in the 11-year study period was close (3-5%) described in the literature, is more common in males and in children and adolescents. Visual acuity was worse for children and adolescents than adults. Bilateral cases were more common than unilateral. The retinitis pigmentosa and juvenile retinoschisis were the most frequent diagnostic hypotheses.
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    Eletrorretinograma de campo total utilizando um protótipo de eletrodo monopolar de microfibra condutiva em pacientes com distrofia retiniana
    (Universidade Federal de São Paulo (UNIFESP), 2015-04-30) Pereira, Josenilson Martins [UNIFESP]; Berezovsky, Adriana [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: The objective of this study was to evaluate the clinical utility of prototype disposable electrode conductive microfiber UNIFESP as a tool evaluation of retinal function in patients with retinal dystrophy, following the standard protocol of the full-field electroretinography (ERG) of International Society for Clinical Electrophysiology of Vision (ISCEV). Methods: This study was approved by the Ethics in Research Federal University of São Paulo under number 1087/08. They participated this study 54 patients, 28 males and 26 females with mean age was 36.17 ± 16.39 years, 31.76 years and median diagnosis Previous retinal dystrophy. All participants underwent the ERG total field using the reusable bipolar electrode Burian-Allen for diagnostic confirmation and further examination and were later using two disposable monopolar electrode conductive microfiber (DTL® imported and UNIFESP prototype). Electroretinograms for the record, the electrodes were randomly selected in two consecutive visits maximum interval of 7 days. The VERIS 5.1.9 EDI system was used to the acquisition and analysis of data. The results were analyzed ERG Separate the linear regression method, using the software Statistical StataSE 11. The retinal dystrophy type was classified based the clinical criteria such as Stargardt's disease, cone dystrophy, retinitis pigmentosa, cone-rod dystrophy and others. The responses of the ERG They were compared with normative data from our own laboratory. Results: The magnitude and quality of the shapes of the waves Electrical obtained with the two electrodes were similar for all ERG responses. The amplitudes obtained with the prototype UNIFESP They tended to be lower than the answers coming from the DTL® for more amplitudes. The regression equations showed that the times culmination obtained from the UNIFESP prototype tended to be later in relation to DTL® electrode for further completion times. although the above results, there was no statistical difference significant for all the parameters of amplitude and time between the completion of DTL® the electrode and UNIFESP prototype. When the analyzes were diseases was separated by greater variability of responses for breadth parameter as compared to the completion time. At amplitudes of resulting responses DTL® electrode tended to be higher in the following diseases: Stargardt disease, cone dystrophy dystrophy and type cone-rod. The regression equations show that the time culmination obtained from the UNIFESP prototype tended to be more late, but there was no statistically significant difference. Conclusions: The results showed that the waveforms obtained with the two types of electrodes were remarkably similar for all ERG responses. The UNIFESP prototype can be an alternative instrument for the clinical record of ERG in the evaluation of retinal function.