Navegando por Palavras-chave "autologous"

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    Autologous grafting of extraocular muscles: experimental study in rabbits
    (Conselho Brasileiro de Oftalmologia, 2005-06-01) Meireles-teixeira, Jorge [UNIFESP]; Bicas, Harley E. A.; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)
    PURPOSE: To evaluate the feasibility of autologous extraocular muscle grafting as a type of muscle expansion surgery. METHODS: The left superior rectus muscle of twenty-nine rabbits was resected and this fragment was attached to the endpoint of the respective right superior rectus (test group). Thereafter, the superior rectus of the left eye was reattached to the sclera (control group). Both groups were examined during different postoperative periods in order to assess their outcomes. RESULTS: The presence of hyperemia was slightly more frequent in the grafted group. Secretion and muscle atrophy were negligible in both groups. Fibrosis was greater in grafted animals. These muscles were weaker than the control muscles, although the force required to split muscular parts was always greater than the physiological one. CONCLUSIONS: This surgical technique was reliable and useful if one intends to achieve muscle expansion without the intrinsic risks of dealing with heterologous/artificial materials.
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    Efeito do enxerto autólogo de pericôndrio costal com butil-2-cianoacrilato em lesão provocada na cartilagem articular do joelho de coelhos
    (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 1999-10-01) Xavier, Mário Sérgio Viana; Souza, Virgínio Cândido Tosta de; Gomes, Paulo de Oliveira [UNIFESP]; Corrêa, José Carlos; Novo, Neil Ferreira [UNIFESP]; Juliano, Yara [UNIFESP]; Faculdade de Ciências Médicas de Pouso Alegre; Universidade Federal de São Paulo (UNIFESP)
    The purpose of this study was to verify the effect of the perichondrium graft with butyl-2-cyanoacrylate in provoked injury in the articular cartilage of rabbit`s knee. Male adult animals were used, divided in 2 groups, called Group A and Group B, with 17 animals each. The Group A animals were reoperated in 4 weeks and the Group B animals in 8 weeks. A 2 cm fragment was taken out from the 7th costal cartilage from which the perichondrium was removed. Two osteo-cartilaginous cylinders were taken out from each medialis condyles of the femurs in the same animal. The articular cartilage of the cylinder was replaced in one side by the perichondrium with a thin layer of sticking-tissue in its external face and only the articular cartilage was removed from the other side. The cylinders were replaced in the femurs. Macroscopically, in Group A, most of the injuries which received the perichondrium were found completely covered with tissue and all the lesions without perichondrium were only partilly covered. In Group B, no macroscopic significant difference in the covering of the injuries was found. Statistically, There was no microscopical significant difference between the injuries with and without perichondrium of the Group A and Group B and neither groups A and B.
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    Estudo do reparo do ferimento de colon com o lado seroso da parede de jejuno, utilizando cianoacrilato e cola de fibrina
    (Colégio Brasileiro de Cirurgiões, 2006-04-01) Fontes, Carlos Edmundo Rodrigues; Taha, Murched Omar [UNIFESP]; Fagundes, Djalma José [UNIFESP]; Prado Filho, Orlando; Ferreira, Marcos Victor; Mardegan, Marino José; Universidade Estadual de Maringá Clínica Cirúrgica; Universidade Federal de São Paulo (UNIFESP)
    BACKGROUND: The present experiment aimed to compare the effect of the use of cyanoacrylate and fibrine glue as adesive on repared colon's wounds with the serosal side of jejuno's wall. METHODS: Forty five male, young adult Wister rats, weighting about 260 g , from the University of Maringá were used.After having been deeply anaesthetized (thiopental was used), the animals underwent a surgery, and a pattern 0,5 cm wound was made, 2 cm away from the cecum, in the caudal location. Group one the wound was repaired by using the jejunal serosal wall and suture.On group two the jejunal serosal wall and fibrine glue was used. Finally on group three the repair was made by using the jejunal serosal wall and cyanoacrylate. The animals were submited to roentgenogram with barium enema on the fourth postoperative day to search for stenosis. On the seventh day, after having been anaesthetized, animals were submited to a laparotomy, segments were collected for both macroscopic and microscopic study. RESULTS: Fibrine glue has shown better result on repair, due to the production of collagen fibres. CONCLUSION: The experiment has come to prove that the wound made on rat's colon can be repaired by the jejunal serosal wall joined to the wound either using the fibrine glue or cyanoacrylate.
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    Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation
    (Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2012-01-01) Majhail, Navneet Singh; Rizzo, James Douglas; Lee, Stephanie Joi; Aljurf, Mahmoud; Atsuta, Yoshiko; Bonfim, Carmem; Burns, Linda Jean; Chaudhri, Naeem; Davies, Stella; Okamoto, Shinichiro; Seber, Adriana [UNIFESP]; Socie, Gerard; Szer, Jeff; Lint, Maria Teresa Van; Wingard, John Reid; Tichelli, Andre; National Marrow Donor Program; Center for International Blood and Marrow Transplant Research; Fred Hutchinson Cancer Research Center; King Faisal Specialist Hospital and Research Center; Nagoya University Graduate School of Medicine; Universidade Federal do Paraná; University of Minnesota; Cincinnati Children's Hospital; Keio University School of Medicine; Universidade Federal de São Paulo (UNIFESP); Hôpital Saint-Louis; Royal Melbourne Hospital; San Martino Hospital; University of Florida College of Medicine; University Hospital Basel
    Advances in hematopoietic cell transplantation (HCT) technology and supportive care techniques have led to improvements in long-term survival after HCT. Emerging indications for transplantation, introduction of newer graft sources (e.g. umbilical cord blood) and transplantation of older patients using less intense conditioning regimens have also contributed to an increase in the number of HCT survivors. These survivors are at risk for developing late complications secondary to pre-, periand post-transplant exposures and risk-factors. Guidelines for screening and preventive practices for HCT survivors were published in 2006. An international group of transplant experts was convened in 2011 to review contemporary literature and update the recommendations while considering the changing practice of transplantation and international applicability of these guidelines. This review provides the updated recommendations for screening and preventive practices for pediatric and adult survivors of autologous and allogeneic HCT.