Navegando por Palavras-chave "Urinary iodine"

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    Correlação entre níveis de iodúria e TSH colhido em cordão umbilical de recém-nascidos do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, São Paulo
    (Sociedade Brasileira de Endocrinologia e Metabologia, 2005-08-01) Alves, Maria Lúcia D arbo; Maciel, Rui Monteiro de Barros [UNIFESP]; Kunii, Ilda [UNIFESP]; Iazigi, Nassim; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)
    The safest and most efficient way to diagnose congenital hypothyroidism (CH) is through screening programs using serum thyroid stimulating hormone (TSH). CH occurs in one in 1:2,300 - 1:5,000 births but higher rates are found in iodine-deficient areas. Iodine was measured in the urine of 141 newborns (87 males and 54 females) from Ribeirão Preto to complement the screening program developed by the School of Medicine of Ribeirão Preto (FMRP-USP) and Federal University of São Paulo (UNIFESP). TSH values did not disclose any case of CH, although we have seen an elevated ratio (0.96%) of calls for retests. The iodine urinary levels ranged from 2.1 to 194µg/l (mean 58.3±36.2µg/l). No differences between the levels of urinary iodine and gender or gestational ages were observed. A negative correlation between urinary iodine and TSH of blood from umbilical cord was found (r= -0.20, p= 0.02).
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    A iodúria de pacientes portadores de tireopatias autoimunes em Santo andré, SP, é comparável à dos indivíduos normais e estável nos últimos dez anos
    (Sociedade Brasileira de Endocrinologia e Metabologia, 2009-02-01) Marino, Maria Angela Zaccarelli; Martins, Lourdes Conceição; Esteves, Roberto Z. [UNIFESP]; Kasamatsu, Teresa S. [UNIFESP]; Maciel, Rui Monteiro de Barros [UNIFESP]; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: Evaluate whether the increase of iodine in the diet would be the triggering factor for auto-immune thyropathies in the city of Santo André, SP. METHODS: Urinary iodine was determined in samples isolated from 58 patients, divided in 4 Groups, and in 13 normal individuals (controls). RESULTS: Urinary Iodine: Group 1 - hyperthyroidism = 203.5±152.71 µg/ L(mean±sd); Group 2 - hypothyroidism = 258.31±148,2 µg/L; Group 3 - chronic auto-immune thyroiditis = 244.29±191.6 µg/L; group 4 (Amiodarone) = 1157.5±261.8 µg/L; Group 5 - Controls = 262.31±146.2 µg/L. On comparing the means of urinary iodine among the groups, the means for groups 1, 2, 3, and 5 did not present significant differences (p>0.05), and all differed from group 4 (p<0.05). Urinary iodine obtained in groups 1, 2, 3 and 5, obtained in 2002-03, is not different from the values determined in students in 1994 in Santo André. CONCLUSION: This study shows evidence that iodine should not be considered as the responsible agent for auto-immune thyropathies in Santo André, and other environmental factors should be investigated.